April 2023 in “Journal of Investigative Dermatology” This study found that PX-12 inhibited the NLRP3 inflammasome and reduced psoriasis-like symptoms in a mouse model, suggesting its potential as a treatment for psoriasis.
January 2025 in “Journal of Skin and Stem Cell” This case report describes a middle-aged man with chronic tophaceous gout who experienced a rare form of non-scarring alopecia due to urate crystal deposition around hair follicles, leading to hair loss that remarkably improved with targeted treatment including allopurinol and lifestyle changes.
April 2026 in “International Journal of Research and Review” This article reviews current literature and suggests that managing gout with early urate-lowering therapy, within a 'treat-to-target' strategy, can help prevent systemic complications and address the rising prevalence of hyperuricemia-related diseases.
252 citations
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April 2009 in “Seminars in Cell & Developmental Biology” This review discusses the complex role of the immune system in tissue repair and regeneration, highlighting its positive and negative influences but reports no new clinical findings.
23 citations
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January 2022 in “Biomaterials Science” Non-viral vectors show promise for safe and effective CRISPR/Cas9 gene editing in treating diseases.