Search

for
Search:

Research

5 / 1000+ results

research From Telogen to Exogen: Mechanisms Underlying Formation and Subsequent Loss of the Hair Club Fiber

81 citations , April 2009 in “Journal of Investigative Dermatology”

This review discusses the shedding phase of the hair cycle, known as exogen, and reports no new findings while analyzing related processes like club fiber formation and release.

research From Wound to Hair Follicle: Unravelling the Mechanisms and Molecular Networks in Wound‐Induced Hair Follicle Neogenesis

September 2025 in “Wound Repair and Regeneration”

This review discusses wound‐induced hair follicle neogenesis and its potential for developing therapies for scar formation, but reports no new clinical results.

research Study of Drug Target Identification and Associated Molecular Mechanisms for the Therapeutic Activity and Hair Follicle Induction of Two Ashwagandha Extracts Having Differential Withanolide Constitutions

September 2023 in “Journal of Nutrition and Metabolism”

This study found that the ashwagandha extracts ASH-Ext1 and ASH-Ext2 show different pharmacological activities in cell models due to their distinct withanolide proportions, highlighting the need for standardized extraction protocols to ensure consistent therapeutic efficacy.

research Molecular Mechanisms Regulating Hair Follicle Development

854 citations , February 2002 in “The journal of investigative dermatology/Journal of investigative dermatology”

This review summarizes recent advances in understanding the molecular mechanisms of hair follicle formation and discusses potential future clinical applications for treating hair loss and skin tumors, but it reports no new clinical results.

research Retinoids in scarless skin regeneration: from molecular mechanisms to therapeutic strategies

September 2025 in “Frontiers in Cell and Developmental Biology”

In this review, retinoids are highlighted as promising agents for promoting scarless skin regeneration by coordinating cellular and molecular processes that suppress fibrosis, enhance re-epithelialization, promote angiogenesis, and enable hair follicle formation, potentially advancing functional skin repair.

View more "molecular mechanisms of hair formation" in research →

Community Join

5 / 533 results

community Minoxidil’s mechanism of action on blood pressure as a potassium channel opening molecule

in Research 83 upvotes 7 months ago

Minoxidil works by opening potassium channels, leading to reduced blood pressure and potential side effects like reflex tachycardia. It is used for hair growth and affects blood pressure at high doses.

community Novel Formulation To Put An End To Hair Loss Once And For All.

in Research/Science 118 upvotes 10 months ago

A pharmacy student proposed a hair loss treatment using minoxidil, finasteride, clascoterone, and tretinoin, aiming for high effectiveness with minimal side effects. Reactions were mixed, with some questioning its feasibility and others showing interest.

community Dht kills hair, but no one says why?

in Finasteride/Dutasteride 40 upvotes 1 year ago

DHT affects hair follicles, contributing to hair loss, but the exact mechanism is unclear. Treatments like finasteride and minoxidil are used to manage hair loss, though they may have side effects and varying effectiveness.

community GT20029 and PP405 the new fin and min that we been waiting for ?

36 upvotes 1 year ago

PP405 and GT20029 are new hair loss treatments with different mechanisms from traditional options like Minoxidil and Finasteride. PP405 targets hair follicle stem cells to reactivate growth, while GT20029 works as an androgen receptor deleter, both requiring ongoing use for effectiveness.

community Topical Dutasteride Experiment

1 upvotes 2 months ago

The user is experimenting with a homemade topical dutasteride formulation to reduce hair loss while minimizing systemic absorption, using MCT oil, almond oil, vitamin E, tea tree oil, and lavender oil. They are monitoring hair growth and side effects, particularly focusing on sexual health, and are open to feedback on their approach.

View more "molecular mechanisms of hair formation" in community →

Learn

7 / 800 results

learn Minoxidil

Vasodilator used on the scalp and, at low doses, as a tablet

learn Osteopontin

Signalling protein studied in hair-growth research

learn KY19382

Experimental compound that activates hair-growth signals, tested only in animals

How does KY19382 actually stimulate dormant hair follicles to grow again? In mouse and cell studies, KY19382 reactivated hair follicles via Wnt/β-catenin signalling; it has never been tested in humans.

learn SCUBE3

Signalling protein made in the hair follicle

How does SCUBE3 work on hair follicles compared to treatments like minoxidil or finasteride? Laboratory research in mice reports that SCUBE3, a protein released by dermal papilla cells, signals dormant follicles to grow through the TGF-β pathway downstream of Hedgehog; minoxidil and finasteride instead work on blood flow to the follicle and on DHT, and unlike SCUBE3 they have decades of human trial data behind them. SCUBE3 has not been tested in human clinical trials and is not available as a medicine.

learn Folic acid

How does folic acid support hair follicle health and growth at a cellular level? Folate is required for the DNA synthesis that fast-dividing hair matrix cells depend on, and severe deficiency causes anemia—but no published trial has given folic acid to people with hair loss and measured the result, so a growth effect is a mechanism, not a finding.

learn Stem Cell Factor

What is stem cell factor and why is it used in hair growth treatments? Stem cell factor is a signalling protein linked to hair colour in lab and mouse studies; it is not a proven hair-loss treatment in people.

learn Procyanidin

What is Procyanidin, and how does it encourage hair growth at the follicle level? In mouse cell and animal studies, procyanidin B-2 increased hair-cell growth. Small human trials, all run by the company that developed the ingredient, reported modest gains; it is not a proven or approved hair-loss treatment.

View more "molecular mechanisms of hair formation" in learn →

Clinics

1 / 2 results

Trichology
Molecular TrichologyPowodów Drugi · PL

Experts

1 / 5 results

SMP Specialist
Hairo Fallas
Newark, NJ, United States

Hairo Fallas