research Intradermal platelet-rich plasma for the treatment of melasma: A clinical and dermoscopic evaluation in dark skin
Intradermal PRP significantly improved melasma in dark skin, with lasting results and no relapse after 3 months.
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research Efficacy and safety of microneedling and oral tranexamic acid in the treatment of facial melasma in women: An open, evaluator-blinded, randomized clinical trial
This study found that both oral tranexamic acid and microneedling improve melasma treatment outcomes when added to standard therapy, with microneedling showing a more sustained remission.
research An Open-Label Comparative Study on the Effects of Platelet-Rich Plasma Therapy with Hydroquinone 4% Versus Hydroquinone 4% Alone in Melasma
This study found that combining platelet-rich plasma with 4% hydroquinone was more effective in reducing melasma symptoms than using hydroquinone alone.
research Low‐fluence Q‐switched Nd: YAG 1064‐nm laser and intense pulsed light for the treatment of melasma
This study found that combining low-fluence Q-switched Nd: YAG laser and intense pulsed light led to faster and more effective melasma treatment compared to using the laser alone, though recurrence still occurred.
research Efficacy and Safety of Platelet-Rich Plasma in Melasma: A Systematic Review
In this study, PRP was found to show promise in treating melasma, offering consistent positive outcomes and satisfaction rates among patients, especially when combined with treatments like hydroquinone and tranexamic acid, though further research is needed to confirm long-term efficacy and safety.
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