community DHT LEVEL IS 700pg/ml AFTER 8 MONTHS OF DUTASTERIDE
The user had high DHT levels after 8 months on dutasteride, questioning the drug's authenticity. They got dutasteride from a legitimate source and will update on progress.
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5 / 931 resultscommunity 18M Diffuse thinning with 7ng/mL Vit D. Is it just the deficiency or is 0.5mg Fin mandatory?
An 18-year-old with diffuse hair thinning is considering switching from a topical Minoxidil 10% + Finasteride 0.1% solution to Minoxidil 5% foam and oral Finasteride 0.5mg, while also addressing vitamin D deficiency and potential scalp inflammation. Users suggest using Nizoral shampoo for inflammation, considering dutasteride for better results, and maintaining vitamin D levels to protect hair follicles from DHT.
community Update Fin 2.5 years + min 3 mnts
User reports using 1.25 mg oral finasteride each morning and 0.75 ml minoxidil topical spray twice a day, along with vitamin D pills. Another user comments on the positive results and asks when finasteride stabilized shedding.
community Has anyone here had their iron or ferritin tested?
Low ferritin levels may contribute to hair loss, and raising ferritin above 40 or 70 ng/mL might help with hair regrowth. Some users also consider zinc deficiency and absorption issues as potential factors.
community AttentionHomemade Topical Fin Users- requesting Feedback
A user is seeking feedback on a homemade topical finasteride formula for hair loss, consisting of 7.5 mg of finasteride, propylene glycol, ethanol, and distilled water. They aim to achieve a 0.0125% solution by applying 2 ml daily.
Research
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research Mechanotransduction in Androgenetic Alopecia: An In Silico Repositioning Study of PIEZO1 + MLCK Axis Using Cofolding and Pilosebaceous Single-Cell Atlas Constraints
This study utilized computational approaches to screen natural compounds targeting a non-androgen pathway involving PIEZO1 and MLCK for treating androgenetic alopecia, identifying several potential candidates for further validation but making no clinical claims.
research Mechanotransduction in Androgenetic Alopecia: An In Silico Repositioning Study of PIEZO1 + MLCK Axis Using Cofolding and Pilosebaceous Single-Cell Atlas Constraints
This in silico study identified potential natural product compounds targeting a non-androgen pathway for promoting hair growth, but further laboratory validation is necessary before any clinical claims can be made.
research Single-cell transcriptomics reveals hair growth retardation mediated by aberrant connective tissue sheath contraction in male androgenetic alopecia
This study combined spatial and single-cell transcriptomics to identify that hypercontractility of the connective tissue sheath activates PIEZO1 in hair follicles, leading to miniaturization in male androgenetic alopecia, and found that inhibiting this contraction improves hair growth in models.
research Aberrant connective tissue sheath contraction drives premature hair follicle regression by inducing progenitor cell depletion in androgenetic alopecia
This study found that targeting connective tissue sheath contraction with an MLCK inhibitor may improve hair growth in androgenetic alopecia by reducing premature hair regression caused by ectopic apoptosis of hair follicle progenitor cells.
research 7472 Estrogen Monotherapy for Testosterone Suppression in Gender Diverse Patients
In this retrospective study, among transfeminine patients aged 19-81 receiving gender-affirming estrogen therapy, 100% achieved testosterone suppression without anti-androgens when serum estradiol exceeded 100pg/mL, predominantly using injectable estrogen.
Clinics
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