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Differential Expression of miR-93 and miR-21 in Granulosa Cells and Follicular Fluid of Polycystic Ovary Syndrome Associating with Different Phenotypes

research Differential Expression of miR-93 and miR-21 in Granulosa Cells and Follicular Fluid of Polycystic Ovary Syndrome Associating with Different Phenotypes

54 citations , November 2017 in “Scientific Reports”

In this study, researchers observed that hyperandrogenic PCOS patients exhibited distinct miRNA and TGFβ signaling gene expression patterns in granulosa cells, suggesting these factors may play a role in PCOS pathogenesis.

research MiR-92a-1-5p and miR-328-3p Are Up-Regulated in Skin of Female Pattern Hair Loss Patients

4 citations , January 2019 in “Annals of Dermatology”

Higher levels of MiR-92a-1-5p and miR-328-3p found in female hair loss patients.

research Prenatal Exposure to Delta-9-tetrahydrocannabinol (THC) Alters the Expression of miR-122-5p and Its Target Igf1r in the Adult Rat Ovary

9 citations , July 2022 in “International Journal of Molecular Sciences”

This study suggests that prenatal exposure to THC may negatively impact ovarian health in rats by altering miRNA expression, potentially leading to reproductive issues such as subfertility or premature reproductive senescence.

research miR‐218‐5p regulates skin and hair follicle development through Wnt/β‐catenin signaling pathway by targeting SFRP2

54 citations , April 2019 in “Journal of cellular physiology”

In this study, miR-218-5p was found to enhance hair shaft growth and positively regulate the Wnt signaling pathway by targeting SFRP2 during skin and hair follicle development.

research miR‐124 promotes neural differentiation in mouse bulge stem cells by repressing Ptbp1 and Sox9

28 citations , November 2018 in “Journal of cellular physiology”

This study found that miR-124 may facilitate the differentiation of hair follicle stem cells into neuronal cells by targeting Sox9 and Ptbp1.

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community 9 month update (0.5 dut/2.5 oral min)

in Progress Pictures 64 upvotes 5 months ago

The user reported improved hair quality and faster growth after switching from finasteride and topical minoxidil to dutasteride and oral minoxidil, despite experiencing significant shedding. They take separate pills daily and are optimistic about future progress.

community Fin and Min shed after 9 months

70 upvotes 3 weeks ago

The user experienced significant hair improvement using oral finasteride and minoxidil but is now facing a secondary hair shedding phase after nine months, possibly linked to weight loss or seasonal changes. Despite concerns, others in the conversation suggest that such shedding is normal and temporary.

community Getting dutasteride in germany

in Finasteride/Dutasteride 18 upvotes 2 years ago

You can get dutasteride in Germany through the Teleclinic app, which sends a prescription to a nearby pharmacy. It costs around 18-19 euros for the prescription and 47 euros for 90 pills of Avodart 0.5.

community I don’t get Finasteride prescribed anymore..

in Finasteride/Dutasteride 57 upvotes 5 months ago

Finasteride is expensive in Germany, but cheaper alternatives are available in other countries like Turkey, Greece, and Russia. Users suggest traveling to these countries or seeking online prescriptions to save money.

community How to get cheap dutasteride in Germany

26 upvotes 2 months ago

Dutasteride can be obtained cheaply in Germany by purchasing a combined pill with tamsulosin and removing the tamsulosin. Users discuss the cost-saving method and other hair loss treatments like finasteride.

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