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research Hair miR‐29a levels are decreased in patients with scleroderma

27 citations , October 2013 in “Experimental dermatology”

In this study, hair shaft miR-29a levels were significantly lower in scleroderma patients than in controls, suggesting that hair microRNAs could serve as independent biomarkers for the disease.

research miR-29 is an important driver of aging-related phenotypes

2 citations , December 2022 in “bioRxiv (Cold Spring Harbor Laboratory)”

In this study, overexpression of miR-29 in mice led to aging-related phenotypes and early lethality, demonstrating its significant role in driving aging processes.

research LncRNA H19 inhibited dermal papilla cell senescence process through miR-29a by targeting Wnt/β-catenin signaling pathway

April 2025 in “Archives of Dermatological Research”

This research observed that overexpression of lncRNA H19 in human dermal papilla cells inhibited cell senescence and maintained hair follicle-inducing abilities by activating the Wnt signaling pathway, suggesting potential therapeutic strategies for androgenetic alopecia.

research miR-29a-5p Inhibits Prenatal Hair Placode Formation Through Targeting EDAR by ceRNA Regulatory Network

May 2022 in “Frontiers in Cell and Developmental Biology”

This study identified that in pig embryos, the miR-29a-5p/EDAR/lncRNA627.1 ceRNA complex plays a critical role in inhibiting hair placode precursor cells proliferation and regulating hair placode formation through the suppression of EDAR expression, which may provide insights into similar mechanisms affecting human hair conditions.

research Molecular crosstalk between lncRNA H19, miR-29a, and JAK2/STAT3 signaling in alopecia areata: a preliminary study

January 2026 in “Cytokine”

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community 14 months - 1mg fin & 5% topical minoxidil results

in Progress Pictures 452 upvotes 4 months ago

Significant hair regrowth was achieved using 1mg finasteride and 5% topical minoxidil over 14 months, with only initial shedding and mild scalp irritation as side effects. Consistency and early treatment are recommended for optimal results.

community Oral Min is much better than topical

in Minoxidil 182 upvotes 1 year ago

Oral minoxidil is seen as more effective and convenient than topical minoxidil for hair regrowth, but it may cause heart-related risks. Users often combine it with finasteride or dutasteride, though some prefer topical treatments due to safety concerns.

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