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research Assessment of miR-19b-3p, miR-182-5p, and miR-155-5p expression and its relationship with alopecia areata severity

March 2025 in “Archives of Dermatological Research”

miR-155-5p can help diagnose and track alopecia areata severity.

research Exploring the effect of hsa-miR-19b-3p on IL-1R1 expression and serum levels in alopecia areata

1 citations , January 2025 in “Archives of Dermatological Research”

This study found that patients with alopecia areata had significantly higher serum IL-1R1 levels, IL-1R1 gene expression, and hsa-miR-19b-3p levels compared to healthy controls, suggesting these could serve as diagnostic and prognostic markers for the disease's severity.

research RETRACTED ARTICLE: Up-regulated lncRNA5322 elevates MAPK1 to enhance proliferation of hair follicle stem cells as a ceRNA of microRNA-19b-3p

9 citations , June 2019 in “Cell cycle/Cell cycle (Georgetown, Tex. Online)”

A specific RNA increases hair stem cell growth and skin healing by affecting a protein through interaction with a microRNA.

research DNMT1-mediated methylation inhibits microRNA-214-3p and promotes hair follicle stem cell differentiate into adipogenic lineages

8 citations , October 2020 in “Stem cell research & therapy”

This study found that DNMT1 promotes adipogenesis in hair follicle stem cells by regulating the miR-214-3p/MAPK1/p-ERK1/2 pathway, suggesting potential applications in stem cell therapy.

research Exosomal microRNA-Based therapies for skin diseases

December 2023 in “Regenerative therapy”

In this review, the authors reported that exosomal miRNA-based therapies showed promising therapeutic effects on nine skin diseases in animal models, with enhanced outcomes observed when using miRNA-overexpressing exosomes compared to natural ones; however, no comparisons to standard treatments were available.

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