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research Identification of Differentially Expressed miRNAs in Alopecia Areata That Target Immune-Regulatory Pathways

April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology”

Researchers found that certain miRNAs, which affect immune system regulation, are differently expressed in mice with a hair loss condition compared to healthy mice.

research Up-Regulation of Androgen Receptor by Heat Shock Protein 27 and miR-1 Induces Pathogenesis of Androgenic Alopecia

January 2022 in “PubMed”

Higher levels of heat shock protein 27 and lower levels of miR-1 can increase AR levels, leading to hair loss in men.

research Role of ASLNC168501 in Regulating Hair Follicle Stem Cell Activity via the AR/miR-128-3p/IGF-1 Pathway

January 2026 in “Stem Cell Research & Therapy”

ASLNC168501 can help treat hair loss by restoring hair follicle stem cell function.

research The AR/miR-221/IGF-1 Pathway Mediates the Pathogenesis of Androgenetic Alopecia

2 citations , January 2023 in “International Journal of Biological Sciences”

A specific pathway involving AR, miR-221, and IGF-1 plays a key role in causing common hair loss.

research A Functional Polymorphism in Interleukin-1α (IL1A) Gene Is Associated with Risk of Alopecia Areata in Chinese Populations

11 citations , March 2013 in “Gene”

A certain genetic variation in the IL1A gene may lower the risk of a hair loss condition in Chinese people.

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Community Join

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community Target Area Hair Count (TAHC) increase comparasion of all future treatments in clinical trial phases

in Research/Science 35 upvotes 1 year ago

Finasteride, Minoxidil, Bioneer CosmeRNA, Technoderma, Kintor, Hope, Breezula, and Follicum treatments showed increases in hair count, with Technoderma showing the highest increase at 24.3 hairs/cm². Amplifica has not yet published results.

community MicroRNA can regrow 90% of lost hair, researchers find

in Treatment 502 upvotes 3 years ago

Researchers finding that microRNA can potentially regrow 90% of lost hair, and the challenges involved in moving this research forward to human trials. Various treatments for hair loss, such as finasteride and minoxidil, have been discussed.

community Baldness Breakthrough: microRNA Stimulates Hair Growth in Aging Follicles

in Technology 320 upvotes 2 years ago

miR-205, a tiny RNA, can stimulate hair growth by softening aging hair follicle stem cells in mice. Future tests aim to see if this can work in humans.

community Has anyone in Germany gotten topical finasteride custom-compounded by a pharmacy?

in Finasteride/Dutasteride 2 upvotes 3 months ago

The conversation is about obtaining custom-compounded topical finasteride in Germany due to side effects from oral finasteride. The user seeks a lower concentration solution separate from minoxidil, and others suggest self-mixing or trying alternatives like dutasteride.

community Before and after Dutasteride/Minoxidil 3 years apart

in Progress Pictures 587 upvotes 2 months ago

A user shared their hair regrowth progress using Dutasteride and topical Minoxidil over three years, noting significant improvements around 4-5 months and continued gains after a year. They reported no major side effects, only an itchy scalp, and emphasized the importance of patience and consistency.

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