This case study indicates that older patients with NMOSD may show favorable clinical improvements with aggressive treatment, even when the intervention is initiated later in the disease course.
47 citations
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November 1982 in “Journal of Cardiovascular Pharmacology” Nitrendipine and nifedipine effectively block muscle contractions, while papaverine relaxes them and minoxidil needs high amounts to work.
57 citations
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February 1975 in “Journal of Clinical Investigation” This study found that minoxidil increased plasma renin activity in patients with hypertension through both an adrenergic mechanism related to heart rate changes and a secondary mechanism unrelated to propranolol.
109 citations
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July 1984 in “Circulation” This study found that long-term minoxidil treatment, despite improving hemodynamics and left ventricular function, was associated with more frequent clinical events and a poorer clinical course in patients with chronic left ventricular failure.
28 citations
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January 2004 in “British Journal of Pharmacology” This study found that minoxidil provides cardioprotective effects in guinea-pig heart cells through selective activation of mitochondrial ATP-sensitive potassium channels.