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research Topical Calcipotriol Therapy for Mild-to-Moderate Alopecia Areata: A Retrospective Study.

38 citations , June 2015 in “PubMed”

This study found that topical calcipotriol may safely and effectively treat mild-to-moderate patchy alopecia areata, with significant hair regrowth observed in the majority of participants over 12 weeks.

research Treatment Effects of Intradermal Botulinum Toxin Type A Injection on Alopecia Areata

24 citations , December 2010 in “Dermatologic surgery”

In this study, BTXA injections did not effectively treat recalcitrant alopecia areata or improve hair regrowth in most patients, suggesting its limitations as an alternative therapy.

research Vitamin D and its Analogs in Treatment of Mild to Moderate Alopecia Areata: Systematic Review and Meta-Analysis.

August 2025 in “PubMed”

In this study, topical and intralesional vitamin D3 and its analogs were found to be effective and safe treatments for mild-to-moderate alopecia areata, achieving a 53.75% success rate, though intralesional vitamin D3 was less effective than other treatments like corticosteroids.

research Health-related quality of life in mild-moderate patchy alopecia areata: Results from the first controlled Phase 2 clinical trial in this population with STS01 (dithranol/ProSilic) and challenges for the future

April 2026 in “medRxiv”

In a phase 2 trial, researchers tested a topical formulation for alopecia areata and found significant hair regrowth with the treatment, but these improvements did not lead to substantial enhancements in health-related quality of life.

research Treatment of moderate-to-severe alopecia areata in adolescents with baricitinib: A retrospective review of 29 patients

January 2023 in “Journal of The American Academy of Dermatology”

This study found that 79% of adolescents with moderate-to-severe alopecia areata treated with baricitinib experienced significant scalp hair regrowth, although further research is needed to confirm these results.

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Community Join

5 / 925 results

community Shiseido (RepliCel) likely to cost around $1000

5 upvotes 10 years ago

RepliCel's potential hair loss treatment may cost around $1000 and aims to protect hair follicles from DHT, possibly reversing some miniaturization. It is not considered a cure and may be most effective in early hair loss stages, with its main advantage over finasteride being the lack of sexual side effects.

community How to Keep Your Hair on Steroids

25 upvotes 2 years ago

To minimize hair loss while using steroids, use finasteride or dutasteride and apply topical anti-androgens like RU58841. Avoid high doses of hair-toxic steroids; prefer testosterone, nandrolone, and boldenone.

community Efficacy and Tolerability of N-Acetyl-Cysteine for Treatment of The Early-onset Androgenetic Alopecia in Men

26 upvotes 4 years ago

N-Acetyl-Cysteine (NAC) was found to improve hair parameters in men with early-onset androgenetic alopecia, showing increased terminal hair count and decreased vellus hair count, with good tolerability. NAC, used alone or with minoxidil, may help due to its antioxidant properties, though its effectiveness can vary among individuals.

community Does anyone else feel that the hype for PP405 has gone?

in Chat 25 upvotes 4 months ago

The conversation discusses skepticism and diminishing excitement around the hair loss treatment PP405 due to unclear trial results. It also mentions other treatments like finasteride, minoxidil, VDPHL01 (extended-release minoxidil), and GT20026 as potential options for hair loss management.

community Why isn’t Topical Dutasteride the “Gold Standard”?

172 upvotes 7 months ago

Topical dutasteride is more effective than finasteride for hair loss but lacks FDA approval and research, leading to less use. Users report varying effectiveness and side effects, with some preferring oral treatments.

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Learn

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learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn Hair Transplant

How much pain will I be in after a hair transplant surgery? Pain after a hair transplant is usually mild to moderate and manageable with medication.

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