April 2026 in “Skin Appendage Disorders” This case report documents the first known occurrence of basal cell carcinoma at the site of repeated microneedling use for male androgenetic alopecia, underscoring the need for further studies on the long-term safety of such devices.
This review highlights that microtrauma, involving small intentional skin injuries, shows promise in stimulating hair growth in non-scarring alopecias by enhancing immune responses and increasing growth factor release, with methods like microneedling and PRP demonstrating efficacy.
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August 2016 in “Aesthetic Surgery Journal” This study found that micro-needling with cosmeceuticals or platelet-rich plasma significantly improved wrinkles, skin laxity, scar softening, and hair growth over 12 months, with minimal side effects, and that the best results occur with pigment and platelet massaging between 5 to 30 minutes post-treatment.
June 2026 in “bioRxiv (Cold Spring Harbor Laboratory)” This study tested a microneedle patch on rabbit and pig models to support skin regeneration, revealing that the treatment accelerated wound closure, reduced scar formation, and promoted hair-bearing tissue and follicle growth, suggesting a trauma-guided framework for skin restoration.
This case study reports the first known instance of basal cell carcinoma developing at the site of repeated microneedling for androgenetic alopecia, suggesting further research is needed to assess the long-term safety of such devices.