32 citations
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September 2018 in “Journal of pharmaceutical sciences” This study extended a skin diffusion model to include a porous pathway, effectively explaining the permeability of both polar and lipophilic solutes through the stratum corneum.
43 citations
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September 2001 in “Scanning” Hair treatments like bleaching increase friction by exposing tiny pores on the hair surface.
February 2025 in “La Pediatria Medica e Chirurgica” In this case study, a 12-year-old boy with Cushing's Disease experienced a complex diagnostic journey; ultimately, a left-side ACTH-secreting microadenoma was identified and treated with gamma knife therapy, normalizing hypercortisolism but resulting in growth hormone deficiency.
5 citations
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April 2023 in “Bioengineering & Translational Medicine” This study found that STAR particles, when applied to human skin, were well tolerated and highly acceptable at various pressures and with repeated daily use, suggesting they may provide a safe and effective method for enhancing drug delivery through the skin.
87 citations
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January 2017 in “PLoS Genetics” This study found that simultaneously inhibiting both KLK5 and KLK7 proteases completely rescued skin barrier defects in a mouse model of Netherton syndrome, suggesting both should be therapeutic targets.