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research Major Histocompatibility Complex Class I Chain-Related Gene A Polymorphisms and Extended Haplotypes Are Associated with Familial Alopecia Areata

44 citations , December 2005 in “Journal of Investigative Dermatology”

This study found significant associations between certain MICA variants and haplotypes with alopecia areata, suggesting MICA as a potential candidate gene linked to the disease's susceptibility and severity.

research Genetics of Diabetes in Childhood

January 2003 in “Springer eBooks”

Certain genes are linked to type 1 and type 2 diabetes in kids, and changes in these genes can also cause other diabetes-related conditions.

research 616 Endoplasmic reticulum stress upregulates NKG2D ligands in the hair follicle

April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study suggests a connection between the unfolded protein response and upregulation of NKG2D ligands in stressed hair follicles, highlighting a potential role of PRDX5 in alopecia areata pathogenesis.

research Alopecia Areata is associated with MICA and an extended HLA haplotype

1 citations , March 2004 in “Journal of the American Academy of Dermatology”

This study reports a strong association between the MICA locus, specifically the MICA∗3-DR∗6-DQ6 haplotype, and Alopecia Areata in families.

Alopecia Areata: Pathogenesis, Genetic Factors, and Treatments Using Mouse Models

research Alopecia Areata

24 citations , January 2008 in “KARGER eBooks”

This review discusses recent advances in understanding the pathogenesis of autoimmune alopecia areata and reports no new clinical results; it highlights potential for developing more effective treatments.

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