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research Effect of Solvent on Stereoselectivity in Pd/C (Type 39K)-Catalyzed Hydrogenation of Methyl 3-Oxo-4-Aza-5-Androstene-17-Carboxylate, a Key Intermediate for Finasteride and Dutasteride
Alcoholic solvent improves selectivity in key intermediate for finasteride and dutasteride synthesis.
research Steroid Hormones: Overview and Medical Applications
Steroid hormones are crucial for body functions and have various medical uses, but their misuse can lead to dependence.
research Novel Inhibitors of 5α-Reductase
New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.
research Azasteroids as Inhibitors of Testosterone 5α-Reductase in Mammalian Skin
Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.
research A Review on Steroidal 5α-Reductase Inhibitors for Treatment of Benign Prostatic Hyperplasia
New treatments for enlarged prostate are being developed, some of which may be more effective than current medications.
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5 / 21 resultscommunity NW5 - 3 Month Results on Dermaroller + Minoxidil + Amplexe (COPPER TRIPEPTIDE-1 Shampoo)
A user shared their positive 3-month results using a treatment for hair loss that includes Dermaroller, Minoxidil, and Amplexe Shampoo. They avoided using finasteride due to its risks.
community 3 years on Dutasteride and still thinning - what would the next logical step be?
The user is experiencing hair thinning despite using Dutasteride and Finasteride and is considering adding Minoxidil. Suggestions include increasing the Dutasteride dose, checking for health issues, and considering a hair transplant.
community New Latanoprost-Based Formula Used by Hollywood Celebrities
A new Latanoprost-based formula used by Hollywood celebrities to treat hair loss, with the formula containing minoxidil, tretinoin, melatonin, azelaic acid, zinc thymulin, vitamin B6, sandalore and methyl vanillate. It also mentions the potential of offering a combined sublingual minoxidil/oral dutasteride option in the future.
community Due to the virus, I can't get rubbing alcohol to sterilize my dermaroller after use. Would Listerine work as an alternative?
The conversation is about using Listerine as an alternative to rubbing alcohol for sterilizing a dermaroller due to unavailability. The ingredients of Listerine are listed to determine its suitability.
community Bile Acid-Mediated DHT Dysregulation Hypothesis
Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.