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GlossaryMatrix Metalloproteinases

enzymes that degrade extracellular matrix proteins

Matrix Metalloproteinases (MMPs) are a group of enzymes that break down proteins in the extracellular matrix, which is the network of molecules surrounding cells. They play a crucial role in tissue remodeling, wound healing, and various physiological processes, but their overactivity can contribute to diseases like arthritis and cancer.

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research Matrix Metalloproteinase-9 Is Involved in the Regulation of Hair Canal Formation

20 citations, September 2010 in “The journal of investigative dermatology/Journal of investigative dermatology”

MMP-9 is essential for proper hair canal formation.

research Expression of Matrix Metalloproteinases and Tissue Inhibitor of Matrix Metalloproteinases in the Hair Cycle

21 citations, May 2016 in “Experimental and Therapeutic Medicine”

MMP-2 and MMP-9 help hair grow, while their inhibitors peak when hair growth slows.

research A Polymorphism in the Matrix Metalloproteinase-1 Gene Promoter Is Associated with the Presence of Polycystic Ovary Syndrome in Caucasian Women

8 citations, May 2005 in “Fertility and Sterility”

A specific gene variation is linked to a higher risk of polycystic ovary syndrome in Caucasian women.

research The Disintegrin/Metalloproteinase Adam10 Is Essential for Epidermal Integrity and Notch-Mediated Signaling

134 citations, January 2011 in “Development”

Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

Successive Release of Tissue Inhibitors of Metalloproteinase-1 Through Graphene Oxide-Based Delivery System Can Promote Skin Regeneration

research Successive Release of Tissue Inhibitors of Metalloproteinase-1 Through Graphene Oxide-Based Delivery System Can Promote Skin Regeneration

9 citations, September 2017 in “Nanoscale Research Letters”

Graphene oxide helps deliver a skin healing agent over time, improving skin and hair follicle regeneration.

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community This serum outperformed Minoxidil in a recent study. Please debunk

23 upvotes 5 years ago

A topical solution called "Multi-Peptide Serum for Hair Density" by The Ordinary Company, which contains several ingredients that are used in alternatives to Minoxidil and was found to have better results than 5% Minoxidil in a study. People who have tried it shared their experiences with the serum as well.

community Comprehensive Microneedling Guide

in Microneedling 290 upvotes 2 years ago

Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.