Search

for
Search:

Did you mean Metabotropic Receptor?

Glossary Metabotropic Receptor

cell receptor triggering internal signaling via G-protein activation

A metabotropic receptor is a type of cell surface receptor that, when activated by a neurotransmitter, initiates a cascade of intracellular events through a signaling molecule called a G-protein. Unlike ionotropic receptors, which form ion channels, metabotropic receptors work indirectly to modulate cellular activity, often resulting in longer-lasting and more diverse effects.

Related Terms

Research

5 / 100 results

Atypical Hippocampal Glutamate Receptor Coupled to Phospholipase D Controlling Stretch-Sensitivity in Primary Mechanosensory Nerve Endings Is Homomeric Purely Metabotropic GluK2

research The atypical ‘hippocampal’ glutamate receptor coupled to phospholipase D that controls stretch‐sensitivity in primary mechanosensory nerve endings is homomeric purely metabotropic GluK2

6 citations , September 2023 in “Experimental physiology”

In this study, researchers identified the PLD-mGluR protein in primary mechanosensory terminals as the homomeric GluK2 kainate receptor, functioning purely metabotropically, which is suggested to be common to various sensory endings.

Glutamate Transporter SLC1A3 Mediates Inter-Niche Stem Cell Activation During Skin Growth

research Transient Ca2+ entry by plasmalogen-mediated activation of receptor potential cation channel promotes AMPK activity

3 citations , November 2022 in “Frontiers in molecular biosciences”

This study suggests that in mice, plasmalogens may enhance hair growth by activating TRPC4 channels, which increases calcium influx and subsequently stimulates AMPK in hair follicles.

View more "metabotropic glutamate receptor" in research →