This study found that loss of the DNA methyltransferase Dnmt3a, but not Dnmt3b, increased carcinogen-induced squamous tumors in murine epidermis, with combined deletion leading to more aggressive and metastatic carcinomas.
The research found that while Dnmt3a and Dnmt3b are not necessary for skin homeostasis in mice, the loss of Dnmt3a increases squamous tumor formation from carcinogens, and combined deletion of both results in more aggressive and metastatic tumors.
September 2025 in “Journal of Ayurveda and Holistic medicine.” This review interprets PCOS as a kapha-predominant disorder within the Ayurvedic framework, characterized by medoduṣhṭi, a feeble state of rasa dhatvagni, and margavaraṇa, but reports no new clinical results.
January 1987 in “Data Archiving and Networked Services (DANS)” This article discusses the metabolism of benzo(a)pyrene in chemical carcinogenesis and reports no new experimental findings.
October 2025 in “University of Zadar Institutional Repository” This article reviews the association between androgenic alopecia and metabolic syndrome, highlighting the importance of early diagnosis and lifestyle changes to manage associated health risks, but reports no new clinical results.