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    Did you mean MEK inhibitors?
    Glossary MEK inhibitors

    block enzymes involved in cell growth signaling pathways

    MEK inhibitors, also known as MEKis or MEK1/2 inhibitors, are a class of drugs that block the activity of the MEK enzymes (MEK1 and MEK2), which are part of the MAPK/ERK signaling pathway. This pathway is crucial for cell division and survival, and its dysregulation is often implicated in various cancers. By inhibiting MEK, these drugs can help to slow down or stop the growth of cancer cells.

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    Research 10 of 430

    1. Dihydrotestosterone Induces Keratinocyte Apoptosis by Activating ERK Signaling In Vivo · 2026
    2. The incidence and management of cutaneous adverse events of the epidermal growth factor receptor inhibitors Postępy Dermatologii i Alergologii · 2017 · 18 citations
    3. Cutaneous Drug Eruptions Associated with the Use of New Oncological Drugs 2012 · 29 citations
    4. When bugs and drugs conspire: driving acneiform skin toxicity 2020 · 1 citations
    5. Sorafenib-induced eruption resembling pityriasis rubra pilaris Journal of the American Academy of Dermatology · 2011 · 21 citations
    6. Cutaneous adverse effects of targeted therapies Journal of the American Academy of Dermatology · 2015 · 149 citations
    7. 329 Mechanisms of Cutaneous Adverse Events during Targeted Cancer Therapy 2022
    8. Targeted therapy in melanoma Clinics in Dermatology · 2013 · 21 citations
    9. Progesterone promotes the survival of newborn neurons in the dentate gyrus of adult male mice Hippocampus · 2009 · 85 citations
    10. Regulatory mechanisms of LGR4 on cancer and cancer stem cell properties Discover Oncology · 2026
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