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This review discusses recent advances in hair regeneration strategies, including mechanical stimulation and complementary therapies like MSC transplantation and platelet-rich plasma, and reports no new clinical results.

In AGA mouse models, this study found that the combination of nickel–copper nanozymes and minoxidil in dissolvable microneedles significantly enhanced hair regeneration and improved the hair follicle microenvironment by reducing reactive oxygen species and increasing vascular density, compared to minoxidil alone.

This narrative review from the authors discusses mechanical scalp stimulation as a potential treatment for androgenetic alopecia, suggesting it has a biologically plausible mechanism but immature clinical evidence; marketing of these devices currently outpaces their supporting data, indicating a need for better-controlled trials.

This narrative review suggests that while mechanical scalp stimulation has a plausible mechanism for aiding androgenetic alopecia, its clinical evidence is insufficient, and the marketing of stimulation devices currently outpaces their efficacy data.