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Mechanical Stretch Upregulates SDF-1α in Skin Tissue and Induces Migration of Circulating Bone Marrow-Derived Stem Cells into the Expanded Skin

research Mechanical Stretch Upregulates SDF-1α in Skin Tissue and Induces Migration of Circulating Bone Marrow-Derived Stem Cells into the Expanded Skin

43 citations, December 2013 in “Stem Cells”

Stretching skin increases a certain protein that attracts stem cells, helping skin regeneration.

research In Silico Modelling of Transdermal Delivery of Macromolecule Drugs Assisted by a Skin Stretching Hypobaric Device

1 citations, November 2022 in “Pharmaceutical research”

The simulation showed that hypobaric pressure improves drug delivery through the skin, but stretching alone doesn't fully explain the increase.

research Epidermal/Dermal Separation Techniques and Analysis of Cell Populations in Human Skin Sheets

1 citations, December 2022 in “The journal of investigative dermatology/Journal of investigative dermatology”

Choosing the right method to separate skin layers is key for good skin cell research.

research Tissue Mechanics in Haired Murine Skin: Potential Implications for Skin Aging

9 citations, February 2021 in “Frontiers in Cell and Developmental Biology”

Older mice have stiffer skin with less elasticity due to changes in collagen and skin structure, affecting aging and hair loss.

research Mechanical Forces in Skin Disorders

65 citations, March 2018 in “Journal of Dermatological Science”

Skin problems can be caused or worsened by physical forces and pressure on the skin.

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community What's your option on complementary treatment

in Product 3 upvotes 5 months ago

The conversation discusses complementary treatments for hair loss while using finasteride and minoxidil, including scalp massagers, scrubs, coconut oil, and vitamin supplements. The user seeks opinions on these additional treatments.

community UPDATE: The theory that explains everything. Please help me make this big!

in Research/Science 449 upvotes 3 years ago

Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.

community We all regret not acting on hair loss sooner. What is something else we can prevent if we act now?

in Chat 94 upvotes 11 months ago

The conversation discusses the importance of early action in various aspects of life such as healthy eating, skincare, fitness, sleep, financial planning, and career development to prevent future health issues, regret, and financial hardship. Specific treatments mentioned include using sunscreen and tretinoin for anti-aging skincare.

community Minoxidil killed my cat - It was just a few licks - Please be super careful with your pets

in Minoxidil 426 upvotes 1 year ago

In this conversation, people discussed how Minoxidil and Finasteride can be toxic to cats if ingested. It was highlighted that even when being careful with application, there is still a risk of poisoning due to the potential for contact between fur/hair and the substances.

community Regrowing my hair/line without Min or Fin September (update) mechanical stimulation

in Finasteride 24 upvotes 6 years ago

The user regrew their hairline using mechanical stimulation, including a 1.5mm derma roller weekly, daily scalp massages, and other treatments like Nizoral, zinc pyrithione, fish oil, and Lipogaine The Big 5. They did not use Minoxidil or finasteride.

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