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research Physical and mechanical cues affecting biomaterial-mediated plasmid DNA delivery: insights into non-viral delivery systems

15 citations , June 2021 in “Journal of Genetic Engineering and Biotechnology”

This review explores biomaterials in non-viral gene delivery systems and highlights the need for more research to better understand how various parameters affect gene delivery processes, without reporting new experimental results.

research Exploring Mechanical Niches Identified by Hair Follicle Compression and How These Transduce Proliferation and Differentiation Cues in Epidermally Derived cells.

January 2019 in “Durham e-Theses (Durham University)”

This study found that JNK plays a dominant role in hair follicle matrix density-dependent proliferation and differentiation, suggesting that collagen bundling affects keratinocyte dynamics.

research The mechanical forces that shape our senses

12 citations , March 2022 in “Development”

This review outlines the role of mechanical forces in the development of sensory organs like eyes and ears, emphasizing insights from recent animal studies and microfabricated organoid systems; it presents no new experimental results.

research Biophysical and Metabolic Cues in the Microenvironment of Skin Wounds: Implications for Stem Cell Behaviour and Epidermal Regeneration

January 2026 in “MEDS Clinical Medicine”

This review highlights emerging evidence that biophysical and metabolic cues, such as oxygen levels and tissue mechanics, significantly influence skin stem cell behavior, which is crucial for developing advanced wound healing therapies beyond traditional infection and inflammation control.

research 439 Gradients of Mesenchymal Stiffness Control Sweat Gland Cell Fate Specification During Morphogenesis

November 2025 in “Journal of Investigative Dermatology”

Mesenchymal stiffness affects sweat gland cell development.

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Community Join

5 / 109 results

community Hair loss research focused on chemistry for decades because we misunderstood the mechanics of growth.

51 upvotes 7 months ago

Hair growth relies on mechanical forces, not just chemicals, with tissue acting like a motor. Minoxidil and finasteride help, but maintaining tissue elasticity and addressing mechanical issues are essential.

community How to deal with mechanically induced shedding

4 upvotes 11 months ago

Minoxidil can cause scalp dryness and flaking, leading to hair shedding when exfoliating. Alternatives like oral Minoxidil, finasteride, and ketoconazole shampoo are suggested to manage these issues.

community Funny Encounter With a Mechanic - Hair Loss Update

in Update 39 upvotes 5 months ago

The user has been taking 3.75mg of finasteride weekly for 8 months, which has improved their hairline and hair texture. They shared a humorous encounter with a bald mechanic who complimented their hair, unaware of the finasteride use.

community Hi-c5 protein, explains why the mechanical tension theory may be correct.

22 upvotes 1 month ago

Hair loss may be influenced by mechanical tension and inflammation, with the hi-c5 protein amplifying androgen effects, leading to follicle miniaturization. Treatments like finasteride, minoxidil, and scalp massages are suggested to manage hair loss.

community Finally jumped on Fin after decent regrowth using all natural regime (mechanical stimulation)

5 upvotes 8 years ago

The user experienced good hair regrowth using natural methods and mechanical stimulation but decided to add finasteride to their regimen for better results. They are optimistic about further regrowth and plan to update on the effects of finasteride, noting no significant side effects so far.

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Experts

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Clinics

1 / 71 results

77
Hair Loss TreatmentsDermatology
Dr. Daniel Cuestas, DermatólogoBogotá · CO

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