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GlossaryTerminal Hair Growth (mature hair growth)

development of thick, pigmented hairs replacing finer vellus hairs

Terminal hair growth refers to the development of thick, pigmented hairs that replace the finer, lighter vellus hairs during puberty or in response to hormonal changes. These mature hairs are typically found on the scalp, face, armpits, and pubic area, and are influenced by androgens, particularly testosterone.

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research In Vitro Hair Follicle Growth Model for Drug Testing

3 citations, March 2023 in “Scientific Reports”

Researchers developed a new method to test hair growth drugs and found that adult cells are best for hair growth, but the method needs improvement as it didn't create mature hair follicles.

research Hair Growth Effect of DN106212 in C57BL/6 Mouse and Its Network Pharmacological Mechanism of Action

June 2023 in “Current Issues in Molecular Biology”

DN106212, an extract from a plant, is better at promoting hair growth than other tested substances by affecting hair growth factors and follicle development.

research The Patch Assay Reconstitutes Mature Hair Follicles by Culture-Expanded Human Cells

11 citations, July 2017 in “Regenerative Medicine”

The patch assay can create mature hair follicles from human cells and may help in hair loss treatments.

research WNT Signaling in the Control of Hair Growth and Structure

271 citations, March 1999 in “Developmental biology”

The research shows that a gene called Wnt3 affects hair growth and structure, causing short hair and balding when overactive.

research Heparan Sulfate Regulates Hair Follicle and Sebaceous Gland Morphogenesis and Homeostasis

42 citations, July 2014 in “Journal of biological chemistry/The Journal of biological chemistry”

Heparan sulfate is important for hair growth, preventing new hair formation in mature skin, and controlling oil gland development.

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community A topical antiandrogen is very necessary to add to the stack, finastride/Dutastride aren't enough to move the needle.

in Update 1 year ago

User added RU and pyrilutamide for hair growth and noticed more baby hairs. Others suggest sticking with fin and min, while some discuss the user's self-image and hair loss severity.

community Alright boys, who’s willing to burn their scalp for science?

in Research/Science 765 upvotes 1 year ago

Researching the effects of scalp trauma on hair growth, with some users suggesting experimenting with a soldering iron or derma pen, and others bringing up studies that suggest this may be an effective treatment.

community I experimented with every medication for hair loss for at least 1 year. my thoughts.

in Treatment 66 upvotes 2 years ago

Minoxidil effective for regrowth but causes dryness; finasteride stops hair loss but may affect hormones; dutasteride powerful but reduces libido; RU58841 thickens hair but expensive and risky; dermarolling improves blood flow and results; aminexil overrated and not effective. Dermarolling beneficial with both minoxidil and finasteride.

community Are there a lot of young folks here on fin?

in Chat 1 year ago

Young people who have used finasteride and minoxidil to treat hair loss, with generally positive results reported by those taking the treatments.

community SCUBE3 and GT20029 could be the closet thing to a cure: Hair Follicle Regeneration and Protection Against DHT

in Research/Science 13 upvotes 1 year ago

SCUBE3 and GT20029 are potential treatments for hair loss, with SCUBE3 stimulating hair growth and GT20029 protecting against DHT. A combined approach using SCUBE3, finasteride or dutasteride, and later GT20029 could provide a comprehensive treatment for androgenetic alopecia.

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