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research Human Epithelial Hair Follicle Stem Cells and Their Progeny: Current State of Knowledge, the Widening Gap in Translational Research and Future Challenges

106 citations, March 2014 in “BioEssays”

We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.

research Methods in Inflammatory Hair Disease Research: Enhanced Multiplex Imaging on Alopecia Areata Tissue Sections

November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology”

New imaging technology can show up to 40 different markers in hair loss tissue, helping to understand hair disease better.

research Developing Human Fetal Skin Demonstrates a Unique Lymphocyte Signature

1 citations, June 2020 in “bioRxiv (Cold Spring Harbor Laboratory)”

Fetal skin has unique immune cells different from adult skin.

research Quantitative Single-Cell Approaches to Stem Cell Research

106 citations, November 2014 in “Cell Stem Cell”

New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.

research Stem Cell Heterogeneity and Plasticity in Epithelia

129 citations, May 2015 in “Cell Stem Cell”

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

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community topical fluridil/eucapil + dut to block all DHT+T from scalp?

in Treatment 7 upvotes 2 years ago

User experienced slow gains with topical fin+min, switched to topical dut+min, and considered adding Eucapil. Another user suggested DUT may be less effective topically due to high molar mass and mentioned Fluridil as a weak anti-androgen that could help.

community Fin raised my estrogen but also testosterone?

in Finasteride/Dutasteride 17 upvotes 9 months ago

A user experienced initial side effects from finasteride, including erectile dysfunction and emotional changes, but later noticed increased muscle mass and assertiveness. Hormonal tests showed elevated estrogen and prolactin levels, which slightly decreased over time; the user plans lifestyle changes to see if they help.

community Tropoelastin injections + verteporfin?

in Research/Science 12 upvotes 1 year ago

The use of tropoelastin injections and verteporfin for hair transplant recipients to help regrow donor area hairs, as well as research done on tropoelastin injections restoring elastin in scarred heart tissue and skin. There are discussions about why it is taking so long to get cosmetic mass produced tropoelastin injectables on the market.

community My Testosterone is less than 1/3rd In 7 Months since I took Finasteride!

in Finasteride/Dutasteride 113 upvotes 1 year ago

A user experienced a significant drop in testosterone levels after taking finasteride, leading to side effects like low libido and muscle mass loss. Despite its effectiveness for hair, the user decided to stop finasteride due to its impact on hormones, preferring to be bald.

community Pyrilutamide is literally my only hope

in Chat 91 upvotes 2 years ago

Considering treatments for hair loss, including Minoxidil, Finasteride, RU58841, Fluridil and Pyrilutamide. The user is weighing the risks of taking unapproved medication before it has been mass produced.

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