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research Acne: a side‐effect of masculinizing hormonal therapy in transgender patients

57 citations , August 2018 in “British Journal of Dermatology”

This review discusses the pathogenesis and treatment of acne in transgender men on testosterone therapy and reports no new clinical results, emphasizing the need for tailored guidelines.

research Dermatologic Care of Hair in Transgender Patients: A Systematic Review of Literature

4 citations , July 2021 in “Dermatology and therapy”

This review examines changes in hair physiology and treatment options for transgender patients on hormonal therapy but reports no new clinical findings, offering treatment recommendations based on the authors' experiences.

research Hormonal, Medical, and Nonsurgical Aspects of Gender Affirmation

5 citations , March 2019 in “Facial Plastic Surgery Clinics of North America”

In this article, the authors reviewed essential terminology and recommendations for creating a welcoming healthcare environment for transgender patients and providing gender-affirming therapy, emphasizing the unique health needs and disparities faced by this population.

research Navigating the Intersection of Hormonal Therapy and Acne Management in Trans Youth

January 2025 in “ARC Journal of Dermatology”

This study discusses the importance of careful dermatological care for transgender youth receiving hormonal therapies, cautioning that acne treatments can interfere with hormone replacement therapy and emphasizing the need for a collaborative interdisciplinary approach to support both acne management and overall well-being.

research EFFECTS OF HORMONAL THERAPY IN TRANSGENDERS

July 2024 in “Biological and Clinical Sciences Research Journal”

This review reports that transgender individuals undergoing hormonal therapy for gender transition face increased risks of cardiovascular disorders, brain tumors, changes in bone density, metabolic disorders, and other health issues, while highlighting the necessity of this therapy for gender transformation.

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community Why is Finasteride seen as “scary” for men, but hormonal birth control is totally normalized for women?

in Finasteride/Dutasteride 757 upvotes 1 year ago

Finasteride is seen as risky for men due to side effects like erectile dysfunction, while hormonal birth control for women is normalized despite its side effects. The discussion points out a double standard influenced by societal and gender norms.

community Does finasteride/dutasteride reverse aging?

in Chat 45 upvotes 1 year ago

Finasteride and dutasteride can improve skin texture and reduce acne by lowering DHT but do not reverse aging. They may enhance skin and hair health for some, but can also cause side effects like dry skin and sexual dysfunction.

community Well… I Did It. Estrogen Saved My Hairline

in Transgender 732 upvotes 2 years ago

OP transitioned and used Spironolactone, Estradiol Valerate, Minoxidil, and dermarolling, resulting in significant hair regrowth. They advise this method may not be suitable for cis men.

community How can this be? I'm on a damn MTF regimen and still getting decimated

in Transgender 1 year ago

The conversation is about a person using minoxidil, finasteride, estrogen, and bicalutamide to combat hair loss, expressing frustration and desperation over their situation. They are advised against using female hormones and encouraged to focus on finasteride and minoxidil, with suggestions to seek therapy for mental health support.

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Learn

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learn Clascoterone

a novel topical treatment that inhibits DHT on androgen receptors

Can I use clascoterone if I'm undergoing gender-affirming hormone therapy? No published clinical trial has tested clascoterone in people on gender-affirming hormone therapy, so its safety in that group is unknown. The FDA label reports low systemic exposure and no described effect on blood testosterone, but it also records HPA-axis suppression and raised potassium in a small minority of subjects.

learn Pyrilutamide

highly targeted anti-androgen that might have minimal systemic effects

learn Bicalutamide

a nonsteroidal anti-androgen, most commonly used orally for women

learn Cyproterone

a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

learn Spironolactone

powerful topical and oral anti-androgen used mostly by women

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