December 2025 in “Indian Journal of Case Reports” This case report highlights an unusual instance of azathioprine potentially triggering rapid alopecia areata and bone marrow suppression in a patient with chronic spontaneous urticaria, with improvement seen after stopping the drug.
July 2025 in “Clinical Dermatology Review” This report presents a rare case where a patient with chronic urticaria developed alopecia areata during azathioprine therapy, accompanied by bone marrow suppression; these effects resolved after stopping the medication, suggesting a possible link between azathioprine and autoimmune activation despite its intended immunosuppressive use.
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October 1982 in “The Journal of Pathology” This study found that high-dose Cyclosporin A in rats led to significant functional and structural changes, including liver, kidney, and immune system alterations, along with behavioral and hematological effects.
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July 1991 in “Irish Journal of Medical Science (1971 -)” Immunosuppressive therapy helps manage autoimmune diseases but carries risks like infection and potential for malignancy.
June 2018 in “Reactions Weekly” A 65-year-old man developed a serious skin cancer linked to a drug he was taking for a fungal infection after a bone marrow transplant.