research Localization of Members of the Notch System and the Differentiation of Vibrissa Hair Follicles: Receptors, Ligands, and Fringe Modulators
Notch-related genes play a key role in the development and cycling of hair follicles.
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5 / 1000+ results research LGR5 Is a Marker of Poor Prognosis in Glioblastoma and Is Required for Survival of Brain Cancer Stem-Like Cells
High LGR5 levels in glioblastoma indicate poor prognosis and are essential for cancer stem cell survival.
research Epidermal Notch Signaling: Differentiation, Cancer, and Adhesion
Notch signalling helps skin cells differentiate and prevents tumors.
research Nail Hyperpigmentation Following Valproic Acid Use: A Rare Case Report
Valproic acid can rarely cause reversible nail discoloration.
research Lithium Therapy Associated with Hidradenitis Suppurativa: Case Report and Review of Dermatologic Side Effects
Lithium therapy may cause skin problems like hidradenitis suppurativa and other side effects, which can improve after stopping the medication.
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5 / 364 resultscommunity 6 months Fin 1mg, Min 5%. Progress feels sooooo slow. This month I added 2% keto shampoo daily, 0.1% trentinoin daily, and weekly derma rolling. Hoping for much better results over the next 6 months.
A user's progress after taking finasteride and minoxidil for 6 months, as well as adding other treatments such as keto shampoo, trentinoin, and derma rolling. Replies include advice to keep going and the suggestion of considering a hair transplant.
community Bryan Johnson shares information on his hair loss stack
Bryan Johnson uses topical dutasteride, minoxidil, and microneedling for hair loss. Users discuss treatment effectiveness and side effects, debating topical versus oral dutasteride efficacy.
community Horrible news, Stemson Therapeutics has shut down
Stemson Therapeutics has shut down, disappointing those seeking a hair loss cure. Current treatments like minoxidil, finasteride, and dutasteride are discussed, with some users experiencing side effects and exploring alternatives like PP405.
community Dermatologist wants me to stop topical min+fin as a teen
A 17-year-old has been using topical minoxidil and finasteride for hair loss but is advised by a dermatologist to taper off due to age concerns. Other users suggest continuing minoxidil but stopping finasteride until at least 18, and consulting a specialized pediatric dermatologist.
community Protac degradation of the androgen receptor in mice shows good efficacy and no systemic drug could be found
The efficacy of degrading the androgen receptor through dermal application in DP cells, a delivery system for topical drugs that involves dissolving microneedles, and rosemary oil as an alternative anti-androgen.