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research Cronkhite-Canada Syndrome Associated with Serrated Adenoma and Malignant Polyp: A Case Report and Literature Review of 13 Cases in Korea

21 citations, January 2013 in “Clinical Endoscopy”

Cronkhite-Canada syndrome (CCS) is a rare condition marked by gastrointestinal and epidermal epithelial disturbances, typically presenting with juvenile-type hamartomatous polyps. In South Korea, 13 CCS cases had been reported without colon cancer until this study. This report detailed the first Korean case of CCS associated with malignant colon polyp and serrated adenoma in a 72-year-old male with symptoms including diarrhea, weight loss, nail dystrophy, hyperpigmentation, and alopecia. Endoscopic examination revealed numerous polyps, and pathology confirmed colon cancer and serrated adenoma. Treatment included Helicobacter pylori eradication and prednisolone.

research Cronkhite-Canada Syndrome Associated with Colon Cancer Metastatic to Liver

5 citations, September 2017 in “Medicine”

A patient with Cronkhite-Canada Syndrome developed colon cancer that spread to the liver, showing the need for regular cancer checks in such patients.

research Keratin Intermediate Filaments in the Colon: Guardians of Epithelial Homeostasis

38 citations, December 2020 in “International journal of biochemistry & cell biology”

Keratin proteins are essential for keeping the cells in the human colon healthy and stable.

research Epigenetics of Colorectal Cancer

218 citations, December 2012 in “Gastroenterology”

Colorectal cancer development involves both genetic changes and epigenetic alterations like DNA methylation and microRNA changes.

research Increased Expression of TSPEAR in Colorectal Cancer Predicts Poor Prognosis

February 2022 in “Research Square (Research Square)”

High TSPEAR levels in colorectal cancer predict worse outcomes.

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community Hair Cloning, Trials were supposed to begin 2020-2021

in Technology 48 upvotes 4 years ago

The conversation discusses hair cloning trials expected to start in 2020-2021 and mentions concerns about potential delays due to the Coronavirus. Treatments like Minoxidil, finasteride, and RU58841 are referenced.

community Oral vs Topical Finasteride for Trans Women

in Transgender 1 month ago

A user is using a Finoxidil topical spray and is curious if oral Finasteride would be more effective, considering they are already on a DHT blocker called Cyproterone. They are concerned about the potential impact of oral Finasteride on their transition.

community Expectations control for SCUBE3

in Research/Science 22 upvotes 6 months ago

SCUBE3, a protein linked to hair growth in moles, was discovered over 25 years ago and is being developed by Amplifica for potential hair loss treatment. Concerns exist about SCUBE3's association with cancer, as it is a protein that promotes cell growth, which could potentially trigger cancer development if used for hair growth therapy.

community Dermatologist told me to quit fin after turning 40

in Finasteride/Dutasteride 194 upvotes 11 months ago

A dermatologist advised a patient to stop taking finasteride (fin) after turning 40 due to potential risk of aggressive prostate cancer. The patient and others in the conversation debated this advice, discussing the relationship between finasteride, prostate cancer, and hair loss, and considering alternatives like topical finasteride.

community 5% Minoxidil after 4 months - started with twice a day but went down to once because I kept forgetting in the morning. Really happy with how it is going!

in Progress Pictures 438 upvotes 1 year ago

The conclusion of the conversation is that the user started using 5% Minoxidil for hair loss and is happy with the progress. They also mentioned being trans and coming off testosterone, which they believe will help prevent further hair loss. Some users suggested using finasteride as well.

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