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GlossaryCancer Cells (Malignant Cells)

abnormal cells that grow uncontrollably and can invade tissues

Cancer cells, also known as malignant cells or neoplastic cells, are abnormal cells that grow and divide uncontrollably, often forming tumors. Unlike normal cells, they can invade nearby tissues and spread to other parts of the body through the bloodstream or lymphatic system, a process known as metastasis. These cells often evade the body's natural mechanisms for cell death and repair, leading to the progression of cancer.

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research Human αβ and γδ T Cells in Skin Immunity and Disease

83 citations, June 2018 in “Frontiers in immunology”

Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.

research A Simple In Vivo System for Studying Epithelialization, Hair Follicle Formation, and Invasion Using Primary Epidermal Cells from Wild-Type and Transgenic Ornithine Decarboxylase-Overexpressing Mouse Skin

13 citations, December 2001 in “Journal of Investigative Dermatology”

Overexpressing ornithine decarboxylase and v-Ha-ras in keratinocytes leads to invasiveness and malignancy.

research Cell Surface B2m-Free Human Leukocyte Antigen Monomers and Dimers: Are They Neo-HLA Class and Proto-HLA?

3 citations, July 2023 in “Biomolecules”

B2m-free HLA variants may be a new class of HLA important in immune responses and diseases.

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community Expectations control for SCUBE3

in Research/Science 21 upvotes 9 months ago

SCUBE3, a protein linked to hair growth in moles, was discovered over 25 years ago and is being developed by Amplifica for potential hair loss treatment. Concerns exist about SCUBE3's association with cancer, as it is a protein that promotes cell growth, which could potentially trigger cancer development if used for hair growth therapy.

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