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Glossary Pseudohermaphroditism

condition where genetic sex differs from external genitalia

Pseudohermaphroditism, also known as false hermaphroditism, is a condition where an individual has the genetic and gonadal sex of one gender (either male or female) but has external genitalia that resemble the opposite sex. For example, a person with male pseudohermaphroditism has XY chromosomes and testes but may have external genitalia that appear female. This condition can result from various genetic, hormonal, or developmental factors.

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research Male pseudohermaphroditism due to 17β-hydroxysteroid dehydrogenase deficiency: Studies on the natural history of the defect and effect of androgens on gender role

98 citations , July 1983 in “Journal of Steroid Biochemistry”

This study in the Arab population of Gaza described pseudohermaphroditism due to 17β-HSD deficiency, where individuals showed marked masculinization after puberty despite inadequate androgen proportions.

research Steroid 17β-hydroxysteroid dehydrogenase deficiency in man: An inherited form of male pseudohermaphroditism

46 citations , December 1992 in “The Journal of Steroid Biochemistry and Molecular Biology”

In this study, researchers observed that testicular 17β-hydroxysteroid dehydrogenase deficiency in an inbred Arab population in Israel leads to genital ambiguity at birth and progressive virilization after puberty.

research Management of neonates and children with male pseudohermaphroditism

21 citations , December 1977 in “Journal of pediatric surgery”

The authors concluded that most male pseudohermaphrodites should be raised as females, recommending early gender assignment and appropriate alterations to better support coping and development.

research MALE PSEUDOHERMAPHRODITISM DUE TO 17β-HYDROXYSTEROID DEHYDROGENASE DEFICIENCY: STUDIES ON THE NATURAL HISTORY OF THE DEFECT AND EFFECT OF ANDROGENS ON GENDER ROLE

January 1983 in “Elsevier eBooks”

Masculinization in affected individuals occurs gradually after puberty due to hormone changes.

research Androgen Biosynthesis and Gene Defects

November 2014 in “Elsevier eBooks”

This article reviews the clinical and biochemical features of genetic mutations affecting dihydrotestosterone production and their potential role in male pseudo-hermaphroditism, but presents no new clinical results.

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community Does creatine really speed up hair loss if you have male pattern baldness?

132 upvotes 11 months ago

Creatine is not proven to cause hair loss, but some report increased shedding, especially with male pattern baldness. Finasteride or minoxidil are suggested to counteract potential hair loss while using creatine.

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