3 citations
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August 2024 In this study, researchers using single nuclei RNA-sequencing found that fibroblasts in deeper layers of mouse skin expressed higher levels of pro-inflammatory genes post-wounding compared to other cells, highlighting their significant role in early inflammation and tissue repair processes.
17 citations
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June 2018 in “Frontiers in Physiology” This study found that acellular dermal matrix scaffolds may facilitate full-thickness skin wound healing by promoting a pro-regenerative immune response through M2 macrophage polarization via the Lamtor1 pathway.
This study found that combining AMD3100 and low-dose FK506 significantly improved and accelerated the healing of diabetic wounds in rats, suggesting a promising therapeutic approach for wound care in diabetes.
September 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” This study indicates that a helminth-derived protein, TGF-β mimic, may accelerate wound healing and promote regenerative processes in skin tissue by interacting with TGF-β receptors.
56 citations
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November 2012 in “Endocrinology” This study found that the absence of vitamin D receptor signaling in mice impairs the inflammatory response to skin injury, particularly affecting macrophage recruitment and granulation tissue formation.