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Did you mean M2 Macrophage Phenotype?

GlossaryM2 Macrophages

immune cells aiding tissue repair and reducing inflammation

M2 macrophages, also known as alternatively activated macrophages, are a type of immune cell that plays a crucial role in tissue repair, wound healing, and anti-inflammatory responses. Unlike M1 macrophages, which are involved in pro-inflammatory and pathogen-killing activities, M2 macrophages help to resolve inflammation and promote tissue regeneration.

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research Nanofiber-Mediated Sequential Photothermal Antibacteria and Macrophage Polarization for Healing MRSA-Infected Diabetic Wounds

18 citations, December 2021 in “Journal of Nanobiotechnology”

The nanofibers effectively treated infected diabetic wounds by killing bacteria and aiding wound healing without toxicity.

ADM Scaffolds Generate a Pro-Regenerative Microenvironment During Full-Thickness Cutaneous Wound Healing Through M2 Macrophage Polarization via Lamtor1

research ADM Scaffolds Generate a Pro-Regenerative Microenvironment During Full-Thickness Cutaneous Wound Healing Through M2 Macrophage Polarization via Lamtor1

17 citations, June 2018 in “Frontiers in Physiology”

ADM scaffolds help skin heal by promoting a healing-type immune response.

research Activation of Astrocytes In Vitro by Macrophages Polarized with Keratin Biomaterial Treatment

6 citations, January 2016 in “Open journal of regenerative medicine”

Keratin treatment reduces astrocyte reactivity and inflammation.

research Mechanisms of Magnesium Oxide-Incorporated Electrospun Membrane Modulating Inflammation and Accelerating Wound Healing

4 citations, October 2022 in “Journal of Biomedical Materials Research Part A”

Magnesium oxide-infused membranes help heal wounds faster by reducing inflammation and promoting skin and hair follicle growth.

research Pro-Regenerative Hydrogel Restores Scarless Skin During Cutaneous Wound Healing

41 citations, September 2017 in “Advanced Healthcare Materials”

A special hydrogel helps heal skin without scars and regrows hair.

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community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 3 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community The Worst Hair Loss Condition You (MAY) have: LPP

in Research/Science 43 upvotes 2 months ago

Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

community Verteporfin and Microneedling

in Treatments 5 months ago

Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.