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GlossaryM2 Macrophages (M2 phenotype)

immune cells aiding tissue repair and reducing inflammation

M2 macrophages, also known as alternatively activated macrophages, are a type of immune cell that plays a crucial role in tissue repair, wound healing, and anti-inflammatory responses. Unlike M1 macrophages, which are involved in pro-inflammatory and pathogen-killing activities, M2 macrophages help to resolve inflammation and promote tissue regeneration.

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research 26SCS-Loaded SilMA/Col Composite Sponge with Well-Arranged Layers Promotes Angiogenesis-Based Diabetic Wound Repair by Mediating Macrophage Inflammatory Response

April 2024 in “Molecules/Molecules online/Molecules annual”

The composite sponge helps heal diabetic wounds by reducing inflammation and promoting new blood vessel growth.

research Single-Cell RNA Sequencing Reveals Cellular and Transcriptional Changes Associated With M1 Macrophage Polarization in Hidradenitis Suppurativa

22 citations, August 2021 in “Frontiers in medicine”

Immune cells in Hidradenitis suppurativa become more inflammatory and may be important for treatment targets.

research Pro-Regenerative Hydrogel Restores Scarless Skin During Cutaneous Wound Healing

41 citations, September 2017 in “Advanced Healthcare Materials”

A special hydrogel helps heal skin without scars and regrows hair.

research Scaffolds for Epithelial and Hair Follicle Regeneration

1 citations, January 2019 in “Elsevier eBooks”

Electrospun matrices help regenerate skin and hair follicles using PCL and collagen scaffolds.

research Nanofiber-Mediated Sequential Photothermal Antibacteria and Macrophage Polarization for Healing MRSA-Infected Diabetic Wounds

18 citations, December 2021 in “Journal of Nanobiotechnology”

The nanofibers effectively treated infected diabetic wounds by killing bacteria and aiding wound healing without toxicity.

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community Just to show you the superiority of dutasteride over finasteride (it's huge)

in Research/Science 58 upvotes 6 months ago

Dutasteride is shown to be significantly more effective than finasteride for treating male androgenic alopecia. Users discuss the difficulty of obtaining dutasteride in some countries and share personal experiences with its effectiveness and side effects.

community 32 M 1 year anniversary on Fin

in Progress Pictures 153 upvotes 8 months ago

A 32-year-old man has been using topical minoxidil for 11 years and oral finasteride for 1 year, along with a dermaroller, and is happy with his hair regrowth progress without experiencing side effects. Commenters are impressed and some are considering starting finasteride after seeing his results.

community (20 M) 1 Year of Progress Fin and Min

in Progress Pictures 1231 upvotes 1 year ago

A 20-year-old man shared his one-year progress using finasteride and minoxidil for hair loss. He experienced no side effects, saw results within weeks, and despite occasional shedding, his hair grew back thicker and in previously bald spots.

community 3 months of hair treatment! I think I’m hyper responsive to my treatment. Finasteride, biotin pills, derma roller with rosemary/jojoba oil applied after, coffee in the morning for caffeine . No diet or alcohol consumption changes.

in Progress Pictures 491 upvotes 1 year ago

The user reports significant hair regrowth after three months using finasteride, biotin pills, a derma roller with rosemary/jojoba oil, and drinking coffee, despite an initial increase in hair shedding. Other users share varied results with similar treatments, with some not experiencing improvements.

community 1.5 years fin plus almost 3 years min, I think I’ve definitely made progress but I’m still not where I want to be, advice?

in Progress Pictures 130 upvotes 11 months ago

The user has been using finasteride for 1.5 years and minoxidil for almost 3 years for hair loss, and has seen some maintenance of hair but not significant regrowth. Suggestions from others include switching to dutasteride, trying oral minoxidil, and considering microneedling or hair fibers for better appearance.

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