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Lysyl Hydroxylase

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research Expansion of Bacterial Phosphatidylglycerol Reactive CD4+ T Cells in Atopic Dermatitis

April 2021 in “Journal of Investigative Dermatology”

People with atopic dermatitis have more CD4+ T cells that respond to a certain bacterial lipid, which may play a role in the skin condition's inflammation.

research A Multicomponent Skin-Targeted COVID-19 Vaccine Elicits Robust Humoral and Cellular Immune Responses

April 2021 in “Journal of Investigative Dermatology”

The new skin-targeted COVID-19 vaccine creates strong immune responses and could improve vaccination methods.

research IL-15 Is an Unexpected Guardian of Hair Follicle Immune Privilege and Promotes Human Hair Growth Ex Vivo

April 2021 in “Journal of Investigative Dermatology”

IL-15 helps protect hair follicles from immune attacks and encourages hair growth.

research Suppression of Fibroblast Proliferation and Lysyl Hydroxylase Activity by Minoxidil

63 citations , September 1987 in “Journal of Biological Chemistry”

Minoxidil slows fibroblast growth and collagen production, potentially treating keloids, hypertrophic scars, and connective tissue disorders.

Characterization of a Partial cDNA for Lysyl Hydroxylase from Human Skin Fibroblasts; Lysyl Hydroxylase mRNAs Are Regulated Differently by Minoxidil Derivatives and Hydralazine

research Characterization of a Partial cDNA for Lysyl Hydroxylase from Human Skin Fibroblasts; Lysyl Hydroxylase mRNAs Are Regulated Differently by Minoxidil Derivatives and Hydralazine

46 citations , December 1992 in “Journal of Investigative Dermatology”

Minoxidil decreases LH expression, while hydralazine has mixed effects on prolyl and lysyl hydroxylase activities.

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community Minoxidil inhibits lysyl hydroxylase which is needed to produce collagen. If I take 2,5...5 mg of minoxidil every day can I cause my skin to age prematurely?

in Minoxidil 31 upvotes 11 months ago

Oral minoxidil is effective for hair loss and unlikely to significantly affect collagen synthesis, making it a safe option without causing premature skin aging. Users report positive hair regrowth without noticeable skin aging.

community For those of you who are getting facial skin side effects (aging, dark circles) from minoxidil, try this, it helped me.

in Minoxidil 10 upvotes 4 years ago

The conversation provides tips to reduce facial skin side effects from Minoxidil, such as changing pillowcases, sleeping on the back, careful application, hydration, and taking breaks. One reply suggests that alcohol in Minoxidil formulations, not Minoxidil itself, may cause skin aging.

community Federal Grant Cuts have impacted PP405 related research

in Technology 460 upvotes 2 weeks ago

Federal funding cuts have delayed PP405 research, affecting hair loss treatment progress, though clinical trials will continue. The discussion highlights PP405's potential compared to minoxidil and finasteride and stresses the importance of government-funded research.

community Minoxidil actually reduces wrinkles

in Research/Science 209 upvotes 9 months ago

Minoxidil may improve or worsen skin quality, with topical forms causing dryness and wrinkles, possibly due to alcohol content, while oral forms have fewer side effects. Some users consider using tretinoin to mitigate negative effects.

community 137 years old and still far more hair than the average r/tressless user

in Satire 1064 upvotes 2 years ago

The post and conversation are about a user claiming to be 137 years old with a full head of hair. Specific treatments mentioned include dutasteride, RU58841, and minoxidil.

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