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research Cell Type-specific Functions of the Lysosomal Protease Cathepsin L in the Heart

56 citations , October 2007 in “Journal of Biological Chemistry”

This study concluded that dilated cardiomyopathy in Ctsl-deficient mice is mainly due to the lack of cathepsin L in cardiomyocytes, with additional heart stress from the fur defect.

The Lysosomal Protease Cathepsin L Is an Important Regulator of Keratinocyte and Melanocyte Differentiation During Hair Follicle Morphogenesis and Cycling

research The Lysosomal Protease Cathepsin L Is an Important Regulator of Keratinocyte and Melanocyte Differentiation During Hair Follicle Morphogenesis and Cycling

146 citations , May 2002 in “The American journal of pathology”

This study found that cathepsin L deficiency in mice led to significant abnormalities in hair follicle development and cycling, including disrupted hair shaft outgrowth and premature hair growth phase entry.

Localization of Cathepsins B, D, L, LAMP-1 and μ-Calpain in Developing Hair Follicles

research Localization of Cathepsins B, D, L, LAMP-1 and .MU.-Calpain in Developing Hair Follicles.

10 citations , January 2001 in “ACTA HISTOCHEMICA ET CYTOCHEMICA”

In this study, autophagy was commonly observed during keratinization in neonate rat hair follicles, suggesting lysosomal proteases and cytoplasmic enzymes may coordinate in hair follicle cell differentiation.

research Analyse de la régulation du gène Hairless et identification des voies de signalisation affectées chez les mutants «bald Mill Hill».

January 2008 in “HAL (Le Centre pour la Communication Scientifique Directe)”

This study identified complex regulatory elements and interactions involving the Hr gene and HR protein that are crucial for hair follicle formation and cycling in mammals.

research Protein degradation: expanding the toolbox to restrain cancer drug resistance

7 citations , January 2023 in “Journal of Hematology & Oncology”

This review discusses how targeting protein degradation processes may help overcome cancer drug resistance, but reports no new clinical results and suggests further research for precise therapeutic strategies.

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learn Liposomal Vitamin E

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community Topical fin - why are people still using alcohol carriers when liposomal is proven to be better?

7 upvotes 1 year ago

Liposomal carriers for topical finasteride offer better targeting, reduced side effects, and less irritation compared to alcohol-based solutions, but availability and cost may limit their use. Minoxidil can dissolve in liposomal carriers, enhancing delivery and stability.

community Why liposomal finasteride and minoxidil may be better than traditional topical solutions.

in Research/Science 2 upvotes 1 year ago

Liposomal formulations of finasteride and minoxidil may enhance drug delivery to the skin and hair follicles more effectively than traditional solutions, potentially improving treatment outcomes. However, more human clinical trials are needed to confirm these benefits.

community Cheapest liposomal topical Dutasteride?

6 upvotes 1 month ago

The conversation is about finding the cheapest liposomal topical dutasteride for hair loss treatment. The user is trying to avoid spending $100 a month and mentions Xyonhealth as an option.

community folligenz liposomal minoxidil sulfate

5 months ago

Folligenz liposomal minoxidil sulfate is being discussed for its effectiveness and cost, with users comparing it to regular minoxidil and tretinoin. One user found no difference with the 10% version and noted that a lower tretinoin percentage reduced side effects like skin peeling.

community is liposomal a proprietary technology? Can it be done at home or at a local pharmacy?

4 upvotes 2 years ago

The conversation discusses the possibility of creating liposomal topical finasteride at home or at a local pharmacy, questioning if it is an expensive or proprietary technology. It also mentions making topical finasteride using alcohol and propylene glycol.

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