13 citations
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August 2024 in “iScience” This study found that 3D spheroid culture reprogrammed mesenchymal stem cells into a uniform immunosuppressive phenotype, suggesting potential therapeutic applications for inflammatory diseases like psoriasis.
This study found that γδTregs can prevent and treat alopecia areata in a mouse model with human scalp transplants, suggesting potential for cell-based therapies in autoimmune diseases like alopecia.
July 2024 in “International Journal of Dermatology Venereology and Leprosy Sciences” This study suggests that topical minoxidil could promote hair regrowth in individuals with alopecia areata by exerting a localized immunosuppressive effect, and that combining minoxidil with other treatments may enhance hair growth outcomes.
18 citations
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March 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, 17β-estradiol increased VEGF production in differentiated THP-1 cells, while dihydrotestosterone counteracted this effect by modulating adenylate cyclase activity.
45 citations
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October 2014 in “Stem cell research & therapy” This study found that using 3D Gel-C6S-HA scaffolds seeded with VEGF165-modified rat hair follicle stem cells enhanced angiogenesis and vascularization in tissue-engineered skin, improving wound healing.
