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GlossaryToxic Epidermal Necrolysis (Lyell's syndrome)

severe skin reaction causing widespread cell death and skin detachment

Toxic Epidermal Necrolysis (TEN) is a rare, life-threatening skin condition characterized by widespread skin cell death, leading to the detachment of the epidermis from the underlying dermis. Often triggered by a severe reaction to medications, it presents with symptoms similar to severe burns, including extensive blistering and peeling of the skin, and requires immediate medical attention.

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research Cutaneous and Ocular Sequelae of Stevens-Johnson Syndrome and Lyell Syndrome

13 citations, December 2010 in “Annales de Dermatologie et de Vénéréologie”

The conclusion is that skin, mucous, and eye problems after Stevens-Johnson syndrome and Lyell syndrome significantly affect patients' lives, highlighting the need for comprehensive care and eye check-ups.

Long-Term Complications of Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis: The Spectrum of Chronic Problems in Survivors Necessitates Multidisciplinary Follow-Up

research Long-Term Complications of Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis: The Spectrum of Chronic Problems in Survivors Necessitates Multidisciplinary Follow-Up

105 citations, February 2017 in “British Journal of Dermatology”

Survivors of Stevens-Johnson syndrome/toxic epidermal necrolysis need ongoing care for various long-term health problems.

research Ocular and Mucocutaneous Sequelae Among Survivors of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in Togo

6 citations, January 2019 in “Dermatology Research and Practice”

Many survivors of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in Togo suffer long-term eye and skin problems.

research Severe Cutaneous Adverse Reactions to Drugs

273 citations, May 2017 in “The Lancet”

Some drugs can cause rare but potentially deadly skin reactions, and early treatment and avoiding the drug again are key.

research Cutaneous Reactions to Drugs

3 citations, July 2017 in “Elsevier eBooks”

Skin reactions are a common reason for emergency visits due to drug allergies, with some severe cases needing intensive care.

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