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research Recent Insight on the Management of Lupus Erythematosus Alopecia

3 citations , March 2021 in “Clinical, Cosmetic and Investigational Dermatology”

This study reviews the types of alopecia associated with lupus erythematosus and discusses treatment challenges, highlighting that non-scarring alopecia is specific to systemic lupus while chronic cutaneous lupus can cause scarring alopecia, with topical corticosteroids and oral antimalarials as primary treatments for cutaneous lupus erythematosus.

research Alopecias in lupus erythematosus

39 citations , October 2018 in “Lupus Science & Medicine”

This article discusses various patterns of hair loss associated with lupus erythematosus, emphasizing the importance of identifying the specific type to aid in classifying systemic lupus erythematosus.

research Non-scarring alopecia of lupus erythematosus: A comprehensive review

August 2023 in “Annales de Dermatologie et de Vénéréologie”

This study provides an updated overview of non-scarring alopecia in lupus erythematosus patients, revealing that diffuse/patchy NSA and lupus hair are strongly associated with systemic activity and respond well to SLE therapy, while progression to scarring alopecia was rare.

research Frontal Fibrosing Alopecia Coexisting with Lupus Erythematosus: Poor Response to Hydroxychloroquine

12 citations , January 2016 in “Skin Appendage Disorders”

This study reports an association between frontal fibrosing alopecia and lupus erythematosus, noting progressive alopecia in the frontotemporal hairline despite treatment with hydroxychloroquine.

research Geometric alopecia associated with lupus erythematosus panniculitis of the scalp: a case series of nine Korean patients

2 citations , May 2018 in “European Journal of Dermatology”

Lupus erythematosus panniculitis on the scalp can cause unique geometric hair loss patterns.

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community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 2 years ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community The Worst Hair Loss Condition You (MAY) have: LPP

48 upvotes 2 years ago

Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

community Alopecia Areata Question

2 upvotes 5 years ago

A user with alopecia totalis, borderline universalis, seeks advice on getting into a Xeljanz trial or appealing insurance for coverage. They experienced significant hair regrowth but are now seeing hair loss again and want to try Xeljanz.

community can someone help me identify these pls

in Treatment 10 months ago

The user is experiencing diffuse thinning and inflammation despite using 2.5mg dutasteride daily, ciclopirox, and ketoconazole shampoos. They are considering treatments like hydroxychloroquine and JAK inhibitors due to suspected scarring alopecia and have faced challenges in obtaining a scalp biopsy.

community Fibrosing alopecia in a pattern distribution

in Research/Science 14 upvotes 2 years ago

A user has been experiencing hair loss for 4 years, with treatments like minoxidil, finasteride, and various supplements proving ineffective. They were diagnosed with fibrosing alopecia in a pattern distribution, a condition that may require a combination of anti-inflammatory and hair growth treatments.

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learn Alopecia Areata

autoimmune disorder causing patchy hair loss

learn Tofacitinib

an immunosuppressant (JAK inhibitor) approved for arthritis and ulcerative colitis, used off-label for severe alopecia areata; it carries an FDA boxed warning

What is tofacitinib, and why is it discussed in relation to autoimmune-related hair loss such as alopecia areata? Tofacitinib is a prescription JAK inhibitor approved for rheumatoid arthritis, psoriatic arthritis and ulcerative colitis — not for alopecia areata. It is discussed for hair loss because a 2014 case report and a 2016 open-label trial reported regrowth in severe alopecia areata, but that use is off-label, the regrowth relapsed after stopping, and the drug carries an FDA boxed warning.

learn GHK-Cu

Heard alopecia areata leaves scar-like spots? Some peptides are helping those areas regrow hair. Alopecia areata patches usually still have living follicles. Peptides are being studied as a possible add-on, but the evidence is small and early. See a dermatologist for treatment.

learn Baricitinib

Baricitinib is a JAK inhibitor FDA-approved in 2022 for adults with severe alopecia areata, where about a third of trial patients on 4 mg regained most scalp hair. It carries an FDA boxed warning, and hair loss usually returns when it is stopped.

learn Salicylic acid

What makes alopecia areata different from other types of hair loss, and can topical Salicylic acid treatments help regrow the affected areas? Alopecia areata is an autoimmune condition, and salicylic acid does not promote hair regrowth.

learn Bimatoprost

Is bimatoprost effective for people with alopecia areata? Bimatoprost may stimulate hair growth but lacks strong evidence for alopecia areata.

learn Centella

Got small bald circles with no warning? Centella creams might calm the area and kickstart new growth. There is no published human trial of Centella asiatica for alopecia areata or any other hair loss; the only hair-related studies are cell-culture work. Community users describe Centella creams as soothing for an irritated scalp, not as regrowth treatments, and a new bald patch needs a doctor's diagnosis first.

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