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GlossaryLuciferase Reporter Gene

gene producing light to measure gene activity in research

A Luciferase Reporter Gene is a gene that codes for the enzyme luciferase, which produces bioluminescence (light) when it reacts with its substrate, luciferin. Scientists use this gene in research to study gene expression and regulation because the light produced can be easily measured, providing a clear indicator of the activity of the gene of interest.

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research The Promoter of an Androgen Dependent Gene in the Hamster Flank Organ

6 citations , May 1997 in “Journal of Dermatological Science”

Researchers found a gene in hamsters that responds to male hormones and may be indirectly controlled by them.

research Generation of iPS-Derived Model Cells for Analyses of Hair Shaft Differentiation

2 citations , September 2017 in “Biotechniques/BioTechniques”

Researchers created a mouse cell line to study hair growth and test hair growth drugs.

research Visualizing Androgen Receptor Activity in Male and Female Mice

89 citations , August 2013 in “PloS one”

Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.

research Stat3 Partly Inhibits Cell Proliferation Via Direct Negative Regulation of FST Gene Expression

3 citations , June 2021 in “Frontiers in genetics”

The protein STAT3 slows down cell growth by blocking the FST gene, which affects hair development in sheep.

research Transcriptional Characteristics Show That miR-144-y/FOXO3 Participates in Embryonic Skin and Feather Follicle Development in Zhedong White Goose

46 citations , August 2022 in “Animals”

miR-144-y and FOXO3 play key roles in skin and feather development in Zhedong White geese.

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