1 citations
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December 2024 in “Case Reports in Dermatology” In this case study, the researchers reported a rare incidence of bilateral hyperpigmented macules on a patient's lower legs, possibly due to cyclophosphamide, suggesting that this chemotherapy drug may directly stimulate hair follicles to cause skin discoloration.
22 citations
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January 2010 in “Clinical Medicine Insights Endocrinology and Diabetes” In this study, hair from forearms showed higher cortisol levels than hair from lower legs, suggesting a localized cortisol response in hair.
9 citations
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August 2016 in “Dermatology Online Journal” This study reports that acquired frictional alopecia of the lower legs, often caused by socks or footwear, is a non-scarring condition that may be more common than previously thought.
5 citations
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January 2014 in “International Journal of Trichology” Hair loss on the lower legs is common in middle-aged men, usually harmless, and doesn't need treatment.
19 citations
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November 2014 in “Journal of Comparative Physiology A” This study found that Cupiennius salei spiders have specialized mechanosensitive hairs on their legs that adaptively respond to joint movements during walking, suggesting a proprioceptive function.