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Clinical Efficacy and Safety of Low-Dose Flutamide Alone and Combined with an Oral Contraceptive for the Treatment of Idiopathic Hirsutism

research Clinical efficacy and safety of low‐dose flutamide alone and combined with an oral contraceptive for the treatment of idiopathic hirsutism

36 citations , November 1995 in “Clinical endocrinology”

This study found that a low dose of flutamide, both alone and combined with an oral contraceptive, effectively reduced hirsutism in women, with the combination showing more lasting effects post-treatment.

research Comparison of a gonadotropin-releasing hormone agonist and a low dose oral contraceptive given alone or together in the treatment of hirsutism.

62 citations , December 1995 in “The Journal of Clinical Endocrinology & Metabolism”

This study found that combining a GnRH agonist with a low-dose oral contraceptive was more effective in treating hirsutism than either agent alone and prevented hypoestrogenic side effects.

research Oral Contraceptives as Anti-Androgenic Treatment of Acne

16 citations , July 2002 in “JOGC/Journal of obstetrics and gynaecology Canada”

This review discusses treatments for female acne, highlighting the effectiveness of low-dose oral contraceptives and noting their similar side effects to placebo; it reports no new clinical results.

research Androgenic effects of oral contraceptives: Implications for patient compliance

22 citations , January 1995 in “The American Journal of Medicine”

This article reviews the negative effects of androgenic disorders and highlights that newer oral contraceptives with less androgenic progestins may reduce these effects and improve compliance, but it reports no new results.

research Hepatotoxicity with low- and ultralow-dose flutamide: a surveillance study on 203 hyperandrogenic young females

29 citations , July 2012 in “Fertility and Sterility”

This study observed that hepatotoxicity is a rare but possible event in hyperandrogenic young females treated with low- and ultralow-dose flutamide, regardless of dose or oral contraceptive use.

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community An argument for why we should take topical Dutasteride seriously

84 upvotes 5 years ago

Topical Dutasteride may halt hair loss and effectively treat androgenic alopecia. Combining low-dose oral Dutasteride with topical application could maximize regrowth and minimize side effects.

community Request for advice, feedback...

in Chat 2 upvotes 1 year ago

The conversation discusses hair loss treatments for a woman experiencing androgenetic alopecia and seborrheic dermatitis, with suggestions including low-dose oral minoxidil, dutasteride, and hormone replacement therapy. The user is seeking advice due to intolerance to spironolactone and topical minoxidil, and concerns about low testosterone and DHT levels.

community SOS – The cure for women = PREGNANCY

2 upvotes 7 months ago

Pregnancy can temporarily reverse hair loss in women, but attempts to mimic pregnancy hormones with treatments like contraceptive pills, spironolactone, estradiol, progesterone, finasteride, and minoxidil have been ineffective. The discussion highlights the need for research into the hormonal mechanisms of pregnancy that affect hair regrowth.

community 18 months Dut - Shed after shed without any gains

in Update 115 upvotes 1 year ago

Dutasteride caused persistent hair shedding and no improvement for 18 months, leading to a switch back to finasteride. The user also uses oral minoxidil and plans to focus on better scalp health.

community We are manipulating our hormones, surely it's prudent to track bloodwork ?

in Finasteride/Dutasteride 64 upvotes 2 years ago

The conversation discusses whether individuals using hair loss treatments like Dutasteride (Dut) or Finasteride (Fin) should regularly check their hormone levels through bloodwork. Some argue it's important to monitor the effects of these medications on hormone levels, while others believe it's unnecessary if there are no side effects, citing cost and practicality concerns.

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learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn Minoxidil

What are the side effects of minoxidil, and can oral minoxidil affect your heart? Minoxidil can cause side effects, and because it was designed as a blood-pressure drug, some of them involve the heart and circulation. Published studies of low-dose oral minoxidil describe mostly mild problems, but fluid around the heart, pericarditis and other serious events have been reported, and the long-term picture is still being studied. Do not start, stop or change minoxidil without a doctor, and if you develop chest pain, a racing heartbeat, shortness of breath, fainting, swelling or rapid weight gain while using it, stop and seek medical care.
From hypertension to hair: the unexpected story of minoxidil Minoxidil was developed as an oral blood-pressure drug and approved as Loniten in 1979; unwanted hair growth in patients led to topical Rogaine, approved for men in 1988 and for women in 1991. Trials support topical minoxidil for pattern hair loss, while low-dose oral minoxidil is a prescription drug used off-label and needs medical supervision.

learn Overview

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Naltrexone

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