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research Comparing the burden of illness in patients with alopecia areata vs atopic dermatitis in the US population from a payer perspective

10 citations , March 2023 in “Journal of Managed Care & Specialty Pharmacy”

This study found that patients with alopecia areata had similar total health care costs as those with atopic dermatitis, despite having fewer comorbidities and prescription medications overall.

research A Layered Framework for Biological Aesthetics: A Narrative Review of Regenerative Medicine in Cosmetic Science

September 2026 in “Cureus”

In this narrative review, the authors discuss regenerative substances like platelet-rich fibrin and mesenchymal stem cells in biological aesthetics, noting that while these methods show promise for regeneration, their safety, effectiveness, and durability remain uncertain due to limited and heterogeneous evidence.

research More than 50 long-term effects of COVID-19: a systematic review and meta-analysis

1250 citations , August 2021 in “Scientific Reports”

In this study, researchers estimated that 80% of patients infected with SARS-CoV-2 experienced at least one long-term symptom, with fatigue being the most common.

research Post‐COVID-19 syndrome: assessment of short- and long-term post-recovery symptoms in recovered cases in Saudi Arabia

39 citations , March 2022 in “Infection”

Many recovered COVID-19 patients in Saudi Arabia still experience symptoms like fatigue and anxiety, especially older adults and those with other health issues.

research Adaptive Triboelectric Nanogenerators for Long-Term Self-Treatment: A Review

17 citations , December 2022 in “Biosensors”

This review discusses recent advancements in triboelectric nanogenerator-based electronics for clinical applications and reports no new experimental results, focusing on customization for chronic disease diagnosis and long-term treatment.

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Community Join

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community The amazing fast pace of PP405.

in Chat 327 upvotes 11 months ago

PP405 is a new hair loss treatment advancing quickly in trials, generating excitement and skepticism about its effectiveness and marketing claims. Some see it as a potential alternative to minoxidil and finasteride, but concerns about long-term effects and the need for DHT blockers persist.

community Why do some doctors just lie to our faces ?

22 upvotes 6 months ago

A 19-year-old is frustrated with doctors giving misleading information about hair loss treatments, specifically finasteride and minoxidil. They plan to self-administer finasteride due to concerns about side effects and lack of supportive medical guidance.

community Clascoterone - what we have right now

24 upvotes 6 months ago

Clascoterone is a topical treatment for androgenetic alopecia, showing modest to moderate hair regrowth, and may be available by 2027-2028. It is considered safer than finasteride, with discussions on its effectiveness compared to RU58841 and pyrilutamide.

community 5 years post hair transplant, 3 months on minoxidil only

326 upvotes 8 months ago

The user had a hair transplant five years ago and started using minoxidil three months ago. Commenters recommend adding finasteride or other DHT blockers to prevent further hair loss and maintain results.

community A Scientific Perspective in Microneedling for Alopecia

48 upvotes 6 years ago

The post and conversation are about microneedling as a treatment for alopecia. It provides a comprehensive review of scientific literature on the technique and its application.

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Learn

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learn Fluocinolone

Can long-term use of Fluocinolone affect the health of hair follicles? There is no long-term human trial measuring what topical fluocinolone does to hair follicles; what is documented is the label's warning about skin atrophy with prolonged use, plus a 2007 mouse study suggesting hair-follicle bulge stem cells do not repair steroid-induced atrophy.

learn Hydrocortisone

What are the risks of long-term hydrocortisone use on the scalp? Dermatology reviews describe long-term topical corticosteroid use as causing skin thinning, delayed healing, greater infection risk, possible suppression of the body's own cortisol, and rebound flares on stopping — and over-the-counter hydrocortisone labels limit use to about a week without a doctor's direction.

learn Osteopontin

Is Osteopontin safe to use long-term in hair growth products? Osteopontin's long-term safety in hair growth products is not yet established.

learn Rapamycin

Is rapamycin safe for long-term use on the scalp, or should it be used in cycles? There is no published human trial of topical rapamycin on the scalp, so nobody knows whether long-term use is safe; the idea of cycling it comes from community practice and theory, not from any study or guideline, and rapamycin for hair loss is an off-label use of a prescription immunosuppressant.

learn Azelaic Acid

Is azelaic acid safe to use daily long-term? Azelaic acid has a long tolerability record on facial skin in acne and rosacea, where side effects are local and usually mild — but for daily long-term scalp use the only trial is one six-month study in 26 women, in which mild itching was the main adverse effect, so long-term scalp safety is not established.

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