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research TRIAMCINOLONE ACETONIDE INTRAMUSCULARLY: EFFECTIVE LONG‐ACTING STEROID THERAPY IN DERMATOLOGIC DISORDERS

10 citations , April 1964 in “Journal of the American Geriatrics Society”

This article reviews triamcinolone acetonide as an intramuscular long-acting steroid therapy for dermatologic disorders but reports no new clinical results.

Pharmacokinetic-Pharmacodynamic Modeling Approach for Dose Prediction of the Optimal Long-Acting Injectable Formulation of Finasteride

research Pharmacokinetic-pharmacodynamic modeling approach for dose prediction of the optimal long-acting injectable formulation of finasteride

6 citations , March 2021 in “International Journal of Pharmaceutics”

This study reported that a subcutaneous injection formulation using PLGA microspheres to release finasteride stably achieved sustained monthly drug delivery without burst release in beagle dogs, with a dose of 16.8 mg identified as optimal for potential first-in-human trials.

research Long-acting microneedle formulations

1 citations , August 2023 in “Advanced Drug Delivery Reviews”

This review discusses various microneedle technologies for long-acting drug delivery, highlighting design considerations and challenges in bringing these minimally invasive devices to market, but it reports no new clinical results.

research A microfluidic application for mass production of drug-loaded polymeric microspheres for a long-acting injectable with IVL-DrugFluidic®, a novel microfluidic microsphere manufacturing platform technology

April 2023 in “OpenNano”

This study demonstrated that the IVL-DrugFluidic® platform is effective for mass-producing finasteride-loaded polymeric microspheres for long-acting injectables, maintaining stable drug release without an initial burst for a month.

research Approaches for estimating the clinical starting dose of new dosage forms: An example of a long-acting injectable formulation of finasteride

December 2022 in “International Journal of Pharmaceutics”

This study estimated the starting dose range for a finasteride long-acting injectable formulation in humans, suggesting that 16.80 mg may be the optimal starting dose.

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Community Join

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community Pyrilutamide for Hair Loss!? (Ft. Steve Cook)

in Satire 4 upvotes 4 months ago

Pyrilutamide is discussed as a potential hair loss treatment, acting as an androgen receptor antagonist. The conversation questions if it can maintain hair long-term without using finasteride.

community Has anyone here been on finasteride for longer than 10 years? If so, have you had any major issues with the medicine please share your experience and how long you have taken the medicine.

in Treatment 112 upvotes 9 months ago

Long-term finasteride use typically slows hair loss, with some users experiencing side effects like sexual dysfunction and depression. Many users also use minoxidil and dutasteride for improved results, though individual responses vary.

community 38yo long time receder - 3.5 months dut/min progress - Am I right to be excited!?

in Progress Pictures 72 upvotes 1 year ago

A 38-year-old user shared progress pictures after 3.5 months of using oral dutasteride, oral minoxidil, dermastamping, and Nizoral shampoo, reporting significant hair regrowth. The user is optimistic about further improvement, while others discuss the effectiveness and side effects of these treatments.

community RU58841 is great, super fast acting!

6 upvotes 2 months ago

RU58841 is praised for its fast-acting effects on hair regrowth, with the user also using finasteride, minoxidil, dutasteride, and GHKcu. Some users report side effects like chest pain, while others see positive results, but it's unclear which treatment is most effective due to multiple compounds being used simultaneously.

community Testicular pain/discomfort....how long will this last? (29/m)

5 upvotes 9 years ago

A user experienced testicular pain after taking finasteride for hair loss and considered lowering the dose to 0.25mg to manage side effects. They also considered adding minoxidil to their routine while seeking advice on whether to continue or stop finasteride.

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Learn

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learn Beta Polypeptide

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Alfatradiol

How long should I wait to see if Alfatradiol is working for me? The one randomised trial and community reports both point to waiting at least 3 to 6 months, and to expecting stabilised shedding rather than regrowth — the published evidence for alfatradiol is a single six-month study in about 100 women.

learn Clascoterone

How long does it take for clascoterone to show results on hair growth? Clascoterone is not approved for hair loss; it is investigational. In the trials reported so far, application was twice daily and increases in terminal hair count were reported at around 6 months, with more sustained change reported between 6 and 12 months.

learn Cyproterone

How long does it take for cyproterone to work on hair loss? There is no reliable published figure for how fast cyproterone works on hair loss: the hair cycle means nothing shows for months, the one randomised trial assessed women at twelve months, and community reports range from about six months to two years — with some people seeing no change at all.

learn Fluridil

How long does it take to see results with Fluridil in progressive hair loss? No published study measures how long fluridil takes to show a visible change; the single double-blind trial (43 men, 2% fluridil) reported a rise in the proportion of hairs in the growth phase at three and nine months, and community reports describe stabilization rather than regrowth.

learn Fluocinolone

Can long-term use of Fluocinolone affect the health of hair follicles? There is no long-term human trial measuring what topical fluocinolone does to hair follicles; what is documented is the label's warning about skin atrophy with prolonged use, plus a 2007 mouse study suggesting hair-follicle bulge stem cells do not repair steroid-induced atrophy.

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Clinics

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