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research The Suppression of Very Long Chain Fatty Acids Is Associated with Skin Carcinogenesis

March 2020 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study suggests that the expression of VLCFA biosynthesis genes is suppressed in skin hyperplasia and cancer, which could influence keratinocyte function.

research Effect of Free Long-Chain Fatty Acids on Anagen Induction: Metabolic or Inflammatory Aspect?

March 2025 in “International Journal of Molecular Sciences”

This study observed that topical application of palmitate or oleate accelerated the onset of the hair growth phase in mice, whereas glycolysis end product lactate delayed it, suggesting metabolic regulation as a promising approach for influencing hair growth.

Bioengineered Plants as a Source of Omega-3 Fatty Acids

research Bioengineered Plants Can Be a Useful Source of Omega-3 Fatty Acids

53 citations , January 2017 in “BioMed research international”

This review discusses the importance of omega-3 fatty acids for human health and explores recent advancements in genetically modifying plants to produce these essential nutrients, but reports no new results.

research Very-long-chain Acyl-CoA Synthetases

191 citations , November 2007 in “Journal of Biological Chemistry”

This review discusses the acyl-CoA synthetase very-long-chain (ACSVL) enzyme family, including its biochemical characteristics, tissue expression, and involvement in lipid metabolism, but presents no new experimental results.

research Maternal western diet causes inflammatory milk and TLR2/4-dependent neonatal toxicity

47 citations , June 2012 in “Genes & Development”

This study found that maternal consumption of a western diet in mice led to toxic milk production, causing inflammation and alopecia in nursing neonates due to Toll-like-receptor activation.

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community Fats on your Head to Stop Hair Loss?

140 upvotes 2 years ago

The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.

community DHT Itch and Oily Scalp Explained (and how to fix it)

90 upvotes 3 months ago

Malassezia overgrowth can worsen oily scalp and inflammation, contributing to hair loss. Treatments include antifungal shampoos, C6/C8 MCT oil, low-dose isotretinoin, finasteride, and dutasteride.

community DHT Harms Scalp Microbiome: DHT Itch is REAL

413 upvotes 1 year ago

Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

community Four Year Progress Update Photos

536 upvotes 1 month ago

A user shared their four-year hair regrowth progress using a regimen of Kirkland Minoxidil foam, Dutasteride, a derma roller, Nizoral shampoo, multivitamins, and a healthy lifestyle. They started seeing significant results after a year with no side effects reported.

community 8 Months of Treatment with Subpar Results

22 upvotes 5 months ago

The user has been using Dutasteride, Minoxidil, Ketoconazole, and RU58841 for hair loss but sees subpar results. Suggestions include adjusting treatments, considering a hair transplant, and addressing scalp inflammation.

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