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learn Tofacitinib
a JAK inhibitor for alopecia areata and other autoimmune conditions
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Research
5 / 191 resultsresearch Disruption of the temporally regulated cloaca endodermal β-catenin signaling causes anorectal malformations
Disrupting β-catenin signaling in certain cells causes anorectal malformations.
research Prediction of gain-of-function and loss-of-function mutations using Combined Annotation Dependent Depletion (CADD)
C-scores can help predict gain-of-function and loss-of-function mutations.
research PCSK9: From Nature’s Loss to Patient’s Gain
Certain genetic mutations can lower bad cholesterol and reduce heart disease risk, leading to effective cholesterol-lowering drugs.
research 457 Impact of alpha-melanocyte-stimulating hormone on mitochondrial function in human dermal fibroblasts
Alpha-MSH affects mitochondrial function, and MC1R mutations may increase skin aging.
research Rapid Characterization of the Functional and Pharmacological Consequences of Cantú Syndrome KATPChannel Mutations in Intact Cells
Kir6.1 mutations in Cantú syndrome increase channel sensitivity and hyperpolarization, while SUR2B mutations do not.
Community Join
5 / 1000+ resultscommunity Is anyone taking creatine while on fin and/or dut?
The conversation discusses the use of creatine while on finasteride and/or dutasteride for hair loss. Opinions vary, with some users reporting no issues and others experiencing accelerated hair loss, suggesting effects are individual.
community My first 8 months and prgress so far, min + fin.
The user started experiencing hair loss at 26 and began treatment with topical minoxidil and oral finasteride. After 8 months, they noticed hair regrowth, especially baby hairs, and remain hopeful for further improvement.
community Any advice for someone starting RU?
Starting RU58841 for hair loss, with suggestions to begin with a lower dose and monitor side effects. Some users recommend sticking with finasteride, minoxidil, and dutasteride instead.
community Does lowering serum prolactin lower prolactin in the scalp?
The conversation discusses whether not masturbating (semen retention) affects hair loss, with opinions varying but generally dismissing the idea. Some participants mention using hair loss treatments like Minoxidil, Finasteride, and RU58841, but the effectiveness and relation to prolactin levels in the scalp are debated.
community Sandalore experiment
A user added sandalore to minoxidil for hair loss, observing some vellus hair growth and less scalp inflammation. Others tried sandalore with mixed results, discussing dosage and effectiveness compared to minoxidil and finasteride.