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    GlossaryScleroderma (Localized Scleroderma)

    chronic autoimmune disease causing skin and connective tissue hardening

    Scleroderma, also known as systemic sclerosis, is a chronic autoimmune disease characterized by the hardening and tightening of the skin and connective tissues. It can affect not only the skin but also internal organs such as the heart, lungs, kidneys, and digestive tract, leading to a range of symptoms from mild to life-threatening. The exact cause is unknown, but it involves an overproduction of collagen, leading to fibrosis and vascular abnormalities.

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      learn Microneedling

      technique to create small wounds in skin to activate collagen production and hair growth

      learn Pyrilutamide

      highly targeted anti-androgen that might have minimal systemic effects

      learn Osteopontin

      signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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      community Is mesotherapy the golden ticket? Any experiences

      in Treatment  3 upvotes 3 weeks ago
      The conversation discusses hair loss treatments, specifically the use of dutasteride, finasteride, and the potential of mesotherapy. The user experiences hair loss despite low DHT levels and considers localized dutasteride treatment, while others suggest consulting a dermatologist and exploring other causes like malabsorption.

      community It’s really unfortunate the CB-03-01 is so expensive.

       14 upvotes 7 years ago
      The conversation discusses the high cost of CB-03-01, a topical antiandrogen for hair loss, which is considered safe and remains localized upon application. It questions whether the expense is justified compared to the lower risks it poses relative to finasteride.

      community How to get rid of dandruff once and for all?

      in Treatment  7 upvotes 3 years ago
      A 20-year-old male using Minoxidil and finasteride for 6 months and keto shampoo for 5 months saw initial improvement in dandruff, but the condition returned. He recently started using 3% salicylic acid shampoo and seeks advice for persistent dandruff, which is oily and localized to the left side of his scalp.