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    GlossaryScleroderma (Localized Scleroderma)

    chronic autoimmune disease causing skin and connective tissue hardening

    Scleroderma, also known as systemic sclerosis, is a chronic autoimmune disease characterized by the hardening and tightening of the skin and connective tissues. It can affect not only the skin but also internal organs such as the heart, lungs, kidneys, and digestive tract, leading to a range of symptoms from mild to life-threatening. The exact cause is unknown, but it involves an overproduction of collagen, leading to fibrosis and vascular abnormalities.

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      learn Microneedling

      technique to create small wounds in skin to activate collagen production and hair growth

      learn Pyrilutamide

      highly targeted anti-androgen that might have minimal systemic effects

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      community It’s really unfortunate the CB-03-01 is so expensive.

       13 upvotes 7 years ago
      The conversation discusses the high cost of CB-03-01, a topical antiandrogen for hair loss, which is considered safe and remains localized upon application. It questions whether the expense is justified compared to the lower risks it poses relative to finasteride.

      community How to get rid of dandruff once and for all?

      in Treatment  6 upvotes 2 years ago
      A 20-year-old male using Minoxidil and finasteride for 6 months and keto shampoo for 5 months saw initial improvement in dandruff, but the condition returned. He recently started using 3% salicylic acid shampoo and seeks advice for persistent dandruff, which is oily and localized to the left side of his scalp.

      community Day 55 of minoxidil and finasteride

      in Is this regrowth?  17 upvotes 1 week ago
      A 20-year-old is using oral and topical finasteride, topical minoxidil, ketoconazole shampoo, rosewater, Adgain tablets, creatine, and derma stamping to address hair loss. There is a debate about creatine's impact on hair loss, with some suggesting it increases DHT, while others disagree.