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      community Bile Acid-Mediated DHT Dysregulation Hypothesis

      in Research/Science  13 upvotes 11 months ago
      Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.

      community What next after 2 years of fin and min?

      in Progress Pictures  18 upvotes 1 year ago
      The user has been using finasteride and minoxidil for hair loss for 2 years and started microneedling, now considering a hair transplant in Mexico. Suggestions include trying dutasteride, oral minoxidil, and various opinions on hair transplant locations and the user's current hair condition.

      community Story time! The Great Unbalding (PP405)

      in Research/Science  210 upvotes 3 days ago
      PP405 is a promising new hair loss treatment that may reactivate dormant hair follicles without side effects. It could surpass traditional treatments like minoxidil and finasteride if successful in further trials.