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research Health Risks Associated with Long-Term Finasteride and Dutasteride Use: It’s Time to Sound the Alarm

17 citations , January 2020 in “The World Journal of Men's Health”

This article discusses the potential health risks associated with long-term use of finasteride and dutasteride for prostate and hair loss treatments, suggesting risks may include non-alcoholic fatty liver disease, insulin resistance, type 2 diabetes, and other metabolic issues.

research Acute And Sub Chronic Toxicity Of Tridax Procumbens In Experimental Animals

17 citations , January 2012 in “IOSR Journal of Environmental Science Toxicology and Food Technology”

This study found that high doses of ethyl acetate extract from Tridax procumbens can have specific toxic effects in rats, including organ damage and significant changes in some serum biochemical parameters.

research Sequential Morphologic and Clinicopathologic Alterations in Dogs with Experimentally Induced Glucocorticoid Hepatopathy

48 citations , August 1981 in “American Journal of Veterinary Research”

This study demonstrates that glucocorticoid hepatopathy in Beagle dogs led to rapid and lasting clinical, morphologic, and biochemical changes, which may aid in the future diagnosis and prognosis of similar conditions.

research Serum and liver tissue biotinidase enzyme activity in rats which were administrated to valproic acid

15 citations , May 2006 in “Brain & development”

The authors concluded that administering biotin may help prevent alopecia caused by reduced biotinidase activity during valproic acid therapy in rats.

research Tea Polyphenol–Zinc Nanocomplexes Alleviate Diquat-Induced Liver and Small Intestine Oxidative Stress in C57BL/6 Mice

August 2025 in “Nanomaterials”

This study found that tea polyphenol–zinc significantly improved intestinal barrier function and reduced liver inflammation and oxidative stress in mice with diquat-induced damage.

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Community Join

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community Thoughts about ORAL ketoconazole? (pills)

8 months ago

Oral ketoconazole is discussed as a potential hair loss treatment, but it poses significant health risks like liver damage and adrenal insufficiency. Users suggest safer alternatives like topical anti-androgens or spironolactone, emphasizing the importance of consulting a specialist.

community Having androgen receptor density and sensitivity at wrong f*ing place

in Satire 7 upvotes 1 year ago

The conversation discusses hair loss treatments, focusing on the use of topical minoxidil, microneedling, finasteride, and dutasteride, while debating the role of testosterone and DHT in hair loss. It also touches on the potential liver health impacts of these treatments and the genetic sensitivity of hair follicles to androgens.

community DHT Itch and Oily Scalp Explained (and how to fix it)

90 upvotes 3 months ago

Malassezia overgrowth can worsen oily scalp and inflammation, contributing to hair loss. Treatments include antifungal shampoos, C6/C8 MCT oil, low-dose isotretinoin, finasteride, and dutasteride.

community Reasons why Topical worked but Oral Minoxidil didn’t?

in Minoxidil 16 upvotes 2 years ago

Some people find topical minoxidil effective for hair loss, but oral minoxidil doesn't work for them, possibly due to absorption issues. Others have had better results with oral minoxidil, suggesting individual responses vary.

community Minoxidil killed my cat. You need to know how deadly this is for pets.

2557 upvotes 1 year ago

Minoxidil is highly toxic to cats and can cause fatal heart issues. Users recommend switching to oral minoxidil to protect pets.

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Learn

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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Clinics

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