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Serenoa Repens (Saw Palmetto) for Lower Urinary Tract Symptoms: The Evidence for Efficacy and Safety of Lipidosterolic Extracts. Part III

research Serenoa Repens (Saw Palmetto) for Lower Urinary Tract Symptoms (LUTS): The Evidence for Efficacy and Safety of Lipidosterolic Extracts. Part III

3 citations , August 2021 in “Uro”

This review concludes that global literature supports the lipidosterolic extract of Serenoa repens as efficacious and safe for treating lower urinary tract symptoms, with some studies showing equivalence to common pharmacologic agents.

Serenoa Repens (Saw Palmetto) for Lower Urinary Tract Symptoms: The Evidence for Efficacy and Safety of Lipidosterolic Extracts. Part I

research Serenoa repens (Saw palmetto) for Lower Urinary Tract Symptoms (LUTS): The Evidence for Efficacy and Safety of Lipidosterolic Extracts. Part I

2 citations , July 2021 in “Uro”

This review discusses the efficacy of the lipidosterolic extract of Serenoa repens for treating lower urinary tract symptoms and reports no new clinical results; the authors propose further examination of the existing literature and guidelines.

A Proprietary Lipidosterolic Extract of Serenoa Repens Promotes Hair Growth Through Mechanisms That Extend Beyond 5-Alpha Reductase Inhibition: Insights From Human Hair Follicle Organ Culture

research A proprietary lipidosterolic extract of Serenoa repens promotes hair growth through mechanisms that extend beyond 5‐alpha reductase inhibition: Insights from human hair follicle organ culture

October 2025 in “International Journal of Cosmetic Science”

This study explored the effects of USPlus® DERM, a bioactive fatty acid extract from Serenoa repens, in promoting hair growth and enhancing hair follicle stem cell stemness in an ex vivo setting, showing potential for both 5‐α reductase-dependent and independent hair loss treatments.

research Serenoa repens (saw palmetto) for Lower Urinary Tract Symptoms (LUTS): The Evidence for Efficacy and Safety of Lipidosterolic Extracts. Part III

July 2021

This review concludes that the global literature supports the efficacy and safety of lipidosterolic extract of Serenoa repens in treating lower urinary tract symptoms, comparable to alpha-blockers and 5α-reductase inhibitors.

research Serenoa repens extracts promote hair regeneration and repair of hair loss mouse models by activating TGF-β and mitochondrial signaling pathway.

24 citations , June 2018 in “PubMed”

This study found that liposterolic extracts of Serenoa repens enhanced hair regeneration and repair in DHT-induced hair loss mouse models, suggesting potential effects comparable to finasteride.

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community Serenoa repens (Saw palmetto)

3 upvotes 6 months ago

Saw palmetto, a 5-alpha reductase inhibitor, caused unexpected side effects like breast changes and altered semen consistency, which resolved after stopping its use. Concerns about similar side effects with finasteride or dutasteride were expressed, and another user reported low libido and depression from saw palmetto.

community From finasteride to Serenoa repens

1 upvotes 10 months ago

The user experienced anxiety and side effects from topical finasteride and is considering switching to saw palmetto. Another user reported no improvement with saw palmetto and experienced liver issues.

community Which Saw Palmetto is good for blocking 5 alpha reductase, Serenoa repens or Chamaerops humilis?

6 years ago

The conversation is about determining which type of Saw Palmetto, either Chamaerops humilis or Serenoa repens, is effective for inhibiting the 5 alpha reductase enzyme related to hair loss. Specific treatments mentioned are Minoxidil, finasteride, and RU58841.

community Topical Serenoa? Anyone tried it?

3 upvotes 7 months ago

The conversation discusses using topical serenoa oil, a natural anti-DHT treatment, for hair loss. It is considered less effective than finasteride and dutasteride but can be added to a routine with topical minoxidil.

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