36 citations
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July 2004 in “Journal of Controlled Release” This study demonstrates that confocal laser scanning microscopy can effectively visualize the rapid diffusion and penetration pathway of a dye into the hair follicle in fresh human scalp skin.
132 citations
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April 2007 in “European journal of pharmaceutics and biopharmaceutics” This study found that an oil-in-water microemulsion of curcumin penetrated deeper into the human stratum corneum and hair follicles compared to an amphiphilic cream.
2 citations
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March 2023 in “Journal of Society of Cosmetic Chemists of Japan” This study found that the "Hair Medulla Care" treatment allows various substances to penetrate hair more effectively, suggesting potential applications for enhancing hair coloring, care, and perming processes.
44 citations
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April 2003 in “European journal of pharmaceutical sciences” This study found that targeting the hair follicle can be increased by using lipophilic drugs combined with surfactant solutions and propylene glycol.
2 citations
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November 2025 in “Pharmaceutics” This study found that a CLSM-based approach could semi-quantitatively assess the transdermal penetration behavior of fluorescent dyes with different lipophilicities, offering a tool for early-stage screening of compound penetration.