research Comparison of Stratum Corneum Penetration and Localization of a Lipophilic Model Drug Applied in an O/W Microemulsion and an Amphiphilic Cream
The microemulsion delivered the dye deeper into the skin than the cream.
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research Permeant Lipophilicity and Vehicle Composition Influence Accumulation of Dyes in Hair Follicles of Human Skin
Lipophilic dyes accumulate more in hair follicles when delivered with surfactant-propylene glycol solutions.
research Penetration and Distribution of Three Lipophilic Probes in Human Skin Focusing on the Hair Follicle
Medium lipophilic substances penetrate skin best, and adding ethanol can increase delivery to hair follicles.
research Differential Stripping: Determination of the Amount of Topically Applied Substances Penetrated into the Hair Follicles
The new "differential stripping" method effectively measures how much substance gets into hair follicles.
research Invasomes: Vesicles for Enhanced Skin Delivery of Drugs
Invasomes effectively deliver drugs through the skin and have potential for improved treatments.
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5 / 26 resultscommunity Regrowth or continued regrowth or continued thinning? [Dutasteride+Oral minoxidil]
A user's concern with their hair thinning while using dutasteride and oral minoxidil, which was switched from finasteride and topical minoxidil after 13 months. The conversation includes advice surrounding potential results, specific treatments used, and side effects.
community Peptides that Stop Hair Loss? | In-depth Literature Review Video
Peptides like TB500, KPV, GHK-CU, and BPC-157 are overhyped for hair growth with limited proven effectiveness in humans. Combining peptides with delivery methods like iontophoresis and sonophoresis shows promise, but many claims remain unproven.
community Topical Dutasteride & Microneedling Works
Topical dutasteride, especially at higher concentrations, can be effective for hair loss when combined with microneedling to enhance absorption. Users discuss the side effects of finasteride and dutasteride, with some preferring topical treatments to avoid systemic side effects.
community Possible solution: 2.5mg DUT for everyone
A user is experimenting with creating a DIY oral Dutasteride solution using raw powder, MCT oil, and Vitamin E to reduce costs. Others discuss their experiences with similar methods and the challenges of sourcing and testing Dutasteride.
community DHT Harms Scalp Microbiome: DHT Itch is REAL
Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.