26 citations,
August 2019 in “Stem Cell Research & Therapy”
PBX1 helps hair stem cells grow and change by turning on certain cell signals and preventing cell death, which may be useful for hair regrowth treatments.
A 22-year-old male is not seeing hair regrowth after using minoxidil and finasteride for a year and additional treatments for three months. Suggestions include improving scalp absorption with sea salt and trying a lipid-based solution, microneedling, and possibly switching to dutasteride if no improvement after 1-2 years.
Dutasteride can lead to increased cholesterol and liver fat. The user is reconsidering its use due to high cholesterol and lipid levels despite a healthy lifestyle.
Minoxidil with alcohol and propylene glycol was more effective than non-alcohol versions, and RU58841 worked best in a non-water-based solution. Oral finasteride showed better results than topical, despite side effects; microneedling and tretinoin worsened hair loss, and PRP was only helpful when younger.
Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.
A user experienced hair thinning after taking Accutane and having a B12 deficiency. They are currently using minoxidil and beclomethasone dipropionate lotion for treatment.